尿毒症患者接受联合式维持性血液透析治疗对其电解质指标、肾功影响  

The Influence of Combined Maintenance Hemodialysis Treatment on Electrolytes and Renal Function in Patients with Uremia

作　　者：陈敢[1] 关昌杰[1] 刘日光[1] 秦曙光[1] CHEN Gan;GUAN Changjie;LIU Riguang;QIN Shuguang(The First People’s Hospital of Guangzhou City,Guangzhou 510180,China;不详)

机构地区：[1]广州市第一人民医院,广东广州510180

出　　处：《中外医学研究》2021年第17期144-146,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:研究尿毒症患者接受联合式维持性血液透析治疗对患者电解质指标、肾功能的影响。方法:随机选择本院2018年10月-2020年3月的尿毒症患者72例,随机分为研究组和常规组,每组36例。研究组接受联合式维持性血液透析治疗,常规组给予简单的维持性血液透析治疗。观察两组电解质(钠、钾、钙、磷离子等)指标及肾功能(肌酐、尿素、β_(2)微球蛋白)的变化水平。结果:治疗前,两组的钠、钾、钙等,以及肌酐、尿素、β_(2)微球蛋白水平比较,差异无统计学意义(P>0.05),且在治疗8周后均有改善,研究组的钠、钾、钙等,以及肌酐、尿素、β_(2)微球蛋白水平明显优于常规组,且研究组并发症发生率低于常规组,差异有统计学意义(P<0.05)。研究组治疗总有效率88.89%,高于常规组的66.67%,两组数据比较差异有统计学意义(P<0.05)。结论:给尿毒症患者实施联合式维持性血液透析可减少并发症发生,也能降低电解质紊乱,减少炎症的发生,提高免疫力,其临床效果显著,值得应用推广。Objective:To study the effect of combined maintenance hemodialysis treatment on electrolytes and renal function in patients with uremia.Method:A total of 72 patients with uremia in one hospital from October 2018 to March 2020 were randomly selected and divided into the study group and the routine group,with 36 cases in each group.Patients in the study group received combined maintenance hemodialysis treatment,while the routine group received simple maintenance hemodialysis treatment.Then the changes of electrolyte(sodium,potassium,calcium,phosphorus ions,etc.)indicators and renal function(creatinine,urea,β_(2) microglobulin)in the two groups were observed.Result:Before the treatment,two groups of sodium,potassium,calcium,creatinine and urea,beta 2 microglobulin horizontal had no significant differences(P>0.05),8 weeks after treatment,the team of sodium,potassium,calcium,creatinine and urea,beta 2 microglobulin level in the study group were significantly better than those in the routine group,and the complications of the study group were lower than those in the routine group(P<0.05).The total effective rate of the study group was 88.89%,which was higher than 66.67%of the routine group,the difference between the two groups was statistically significant(P<0.05).Conclusion:The implementation of combined maintenance hemodialysis for patients with uremia can reduce the occurrence of complications,reduce electrolyte disturbances,reduce inflammation,and improve immunity.Its clinical effect is significant and it is worthy of application and promotion.

关 键 词：尿毒症 联合式维持性血液透析 电解质 肾功能 并发症 

分 类 号：R692.5[医药卫生—泌尿科学]