沙美特罗替卡松加家庭氧疗在稳定期慢阻肺患者中的实施意义  

The significance of salmeterol fluticasone and home oxygen therapy in patients with stable chronic obstructive pulmonary disease

作　　者：陈德才 CHEN De-cai(Department of Respiratory Medicine,Shenyang Fourth People’s Hospital,Shenyang 110031,China)

机构地区：[1]沈阳市第四人民医院呼吸内科,110031

出　　处：《中国实用医药》2021年第17期136-138,共3页China Practical Medicine

摘　　要：目的探讨沙美特罗替卡松加家庭氧疗在稳定期慢性阻塞性肺疾病(慢阻肺)患者中的实施效果。方法78例稳定期慢阻肺患者,按随机投掷法分为参照组和研究组,每组39例。参照组在基础治疗后给予沙美特罗替卡松吸入治疗,研究组在参照组基础上联合开展家庭氧疗治疗。对比两组患者治疗前后呼吸困难、咳嗽、咳痰等症状评分以及肺功能指标[第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、FEV1/FVC]水平。结果治疗后,研究组患者呼吸困难、咳嗽、咳痰评分分别为(1.26±0.23)、(0.74±0.24)、(0.68±0.21)分,均低于参照组的(1.83±0.27)、(1.12±0.28)、(1.04±0.26)分,差异有统计学意义(P<0.05)。治疗后,研究组患者FEV1、FVC、FEV1/FVC水平高于参照组,差异有统计学意义(P<0.05)。结论沙美特罗替卡松联合家庭氧疗在稳定期慢阻肺患者中的实施效果显著,可同步改善患者临床症状并提升肺功能,可临床推广。Objective To discuss the effect of salmeterol fluticasone and home oxygen therapy in patients with stable chronic obstructive pulmonary disease.Methods A total of 78 patients with stable chronic obstructive pulmonary disease were randomly divided into reference group and research group,with 39 cases in each groups.The reference group was treated with salmeterol ticasone inhalation therapy after the basic treatment,and the research group was treated with home oxygen therapy on the basis of the reference group.The dyspnea,cough,sputum expectoration,and lung function indexes[forced expiratory volume in the 1st second(FEV1),forced vital capacity(FVC),FEV1/FVC]levels before and after treatment were compared between the two groups.Results After treatment,the dyspnea,cough and sputum score of the research group were(1.26±0.23),(0.74±0.24)and(0.68±0.21)points,which were lower than(1.83±0.27),(1.12±0.28),(1.04±0.26)points of the reference group,and the difference was statistically significant(P<0.05).After treatment,the levels of EFV1,FVC and FEV1/FVC of the research group were higher than those of the reference group,and the difference was statistically significant(P<0.05).Conclusion Combination of salmeterol fluticasone and home oxygen therapy has remarkable effect on patients with stable chronic obstructive pulmonary disease,which can simultaneously improve the clinical symptoms and pulmonary function of patients,and can be promoted clinically.

关 键 词：沙美特罗替卡松 家庭氧疗 稳定期慢性阻塞性肺疾病 症状评分 肺功能 

分 类 号：R563.9[医药卫生—呼吸系统]