中文文献糖尿病前期干预效果的网状Meta分析  

A network meta analysis of the intervention effect of Chinese literature on prediabetes

作　　者：郭丽娜[1] 杨娟[2] 孙俐[3] GUO Lina;YANG Juan;SUN Li(Tianjin Medical University Chu Hisen-I Memorial Hospital,Tianjin Institute of Endocrinology,NHC Key Laboratory of Hormones and Development,Tianjin Key Laboratory of Metabolic Diseases,Tianjin,300134;Jilin Medical University,Jilin City,Jilin Province,132013;Tianjin Medical University,Tianjin,300070,China)

机构地区：[1]天津医科大学朱宪彝纪念医院,天津市内分泌研究所,国家卫健委激素与发育重点实验室,天津市代谢性疾病重点实验室,天津300134 [2]吉林医药学院,吉林吉林132013 [3]天津医科大学,天津300070

出　　处：《吉林医药学院学报》2021年第4期257-260,共4页Journal of Jilin Medical University

基　　金：天津医科大学朱宪彝纪念医院科研基金(2011DX01).

摘　　要：目的比较药物和生活方式干预治疗糖尿病前期的疗效。方法检索中国知网、维普和万方数据库,比较不同药物和生活方式干预治疗糖尿病前期的效果。结果共纳入59篇中文文献,包括8094例患者。结果显示,多种药物和生活方式单独或联合干预糖尿病前期人群对2型糖尿病发病率的干预效果不同;饮食、运动、健康教育和吡格列酮联合组干预措施的累计排序概率图下面积最大(83.9),对于预防糖尿病前期发展为2型糖尿病最为有效。结论饮食、运动、健康教育和吡格列酮联合干预对降低糖尿病前期人群的2型糖尿病发病率效果最好。Objective To compare the efficacy of drug and lifestyle intervention in the treatment of prediabetes.Methods The databases of CNKI,VIP and Wanfang were searched.Objective to compare the effect of different drugs and lifestyle intervention in the treatment of pre diabetes.Results A total of 59 Chinese literatures were included,including 8094 patients.The results showed that the intervention effect of multiple drugs and lifestyle alone or jointly on prediabetes incidence rate of type 2 diabetes was different.The area under the cumulative probability chart of intervention measures in diet,exercise,health education and pioglitazone combination group was the largest(83.9),which was the most effective for preventing pre diabetes from developing into type 2 diabetes.Conclusion Diet,exercise,health education and pioglitazone combined intervention can reduce the incidence rate of type 2 diabetes in pre diabetes.

关 键 词：药物 生活方式 糖尿病前期 预防 

分 类 号：R587.1[医药卫生—内分泌]