飞行训练过程中高载荷(+Gz)对飞行员心肌细胞损害的影响  

The effects of high+Gz exposure on myocardial damage in pilots in flight training

作　　者：贺旭华 朱俐俐 朱曦 文江龙 熊汨 He Xu-hua;Zhu Li-li;Zhu Xi;Wen Jiang-long;Xiong Mi(The 921th Hospital of PLA Joint Logistics Support Force/Second Affiliated Hospital of Hunan Normal University,Changsha 410003,China)

机构地区：[1]中国人民解放军联勤保障部队第九二一医院/湖南师范大学第二附属医院空勤科,长沙410003

出　　处：《湖南师范大学学报（医学版）》2021年第2期113-115,共3页Journal of Hunan Normal University(Medical Sciences)

摘　　要：目的:观察飞行员在飞行不同训练科目时高载荷(+Gz)对飞行员心肌细胞的损伤。方法:选13名男性飞行员飞行训练中完成特定飞行科目,训练科目最高+Gz可达6~7G,持续时间5~10s,训练当天及训练结束后第二日清晨分别留取受试者肘静脉血检测肌酸激酶(CK)、肌酸激酶同工酶MB型(CK-MB)、肌红蛋白(Mb)、肌钙蛋白T(TnT)、乳酸脱氢酶(LDH)观察前后的变化。结果:飞行员+Gz暴露后,肌酸激酶(CK)由(118.2±14.3)U/L明显高于飞行前(178.5±28.1)U/L;肌红蛋白(MB)由飞行前(55.09±2.26)ng/mL升高至飞行后(77.66±7.45)ng/mL;TnT暴露后在正常值范围内稍有升高,不具统计学意义。肌酸激酶同工酶MB型、乳酸脱氢酶无明显升高。结论:实际飞行训练时+Gz暴露对飞行员心肌细胞有损害。Objective To explore the after effects of high+Gz exposure on myocardial damage in humans.Methods Select 13 male pilots in flight training to complete different flying course,high+Gz training course at up to 6~7G,maintain 5~10s.The serum myocardial enzymes that including creatine kinase(CK),creatine kinase-MB(CK-MB),myohemoglobin(Mb),Troponin T(TnT),lactic acid dehydrogenase(LDH),were measured before and the next morning after ex posure.Results Blood CK level had increase,from(118.2±14.3)U/L to(178.5±28.1)U/L after high Gz exposure.Blood MB lever had icraese,from(55.09±2.26)U/L to(77.66±7.45)U/L after high Gz exposure.Blood TnT,CK-MB,LDH level was lower than normal level after+Gz exposure.Conclusion High GZ exposure during actual flight training can damage pilots’cardiomyocytes.

关 键 词：飞行员 加速度 高载荷(+Gz) 心肌损害 心肌酶 

分 类 号：R852.21[医药卫生—航空、航天与航海医学]