2型糖尿病中医药治疗的脏腑归属  

The Attribution of Zangfu Organs in the Treatment of Type 2 Diabetes Mellitus with Chinese Medicine

作　　者：夏城东[1] XIA Cheng-dong(Department of Endocrinology,Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing,100091)

机构地区：[1]中国中医科学院西苑医院内分泌科,北京100091

出　　处：《中国中西医结合杂志》2021年第6期748-751,共4页Chinese Journal of Integrated Traditional and Western Medicine

基　　金：国家自然科学基金资助项目(No.81373581)。

摘　　要：笔者在中医药"厥阴消渴""肠肝相通"学说的基础上,结合现代医学肠—肝轴理论和2型糖尿病(T2DM)患者临床诊治实践,创新性提出:"肠热肝寒,厥阴枢机不利是T2DM的主要病机。"治以清肠热,温肝散寒,调和厥阴枢机,对乌梅丸进行化裁应用,创制连梅肉桂方(黄连、乌梅、肉桂)治疗T2DM患者取得较佳效果。本文从调节肠道菌群,改善肝脏胰岛素抵抗入手,进一步探讨T2DM中医学病理生理及中药药物作用机制。Based on the theories about"consumptive thirst syndrome of Jueyin"and"Intestine-Gan connection"in Chinese medicine,together with the current knowledge of the gut-liver axis and the clinical treatments which were conducted on type 2 diabetes mellitus(T2DM),the author first proposed that T2DM patients were diagnosed as having syndrome of heat in intestine and cold in Gan,and treated with the method of clearing heat in intestine,warming cold in Gan and reconciling intestine and Gan.Lianmei Rougui Decoction,composed of Fructus mume,Rhizoma coptidis and Cortex cinnamomi,was used with good clinical effect.The pathogenesis of heat in intestinal and cold in Gan in T2DM could provide a new strategy for Chinese medicine in treatment of T2DM.The pathophysiology of Chinese medicine of T2DM patients and the associated mechanism of Lianmei Rougui Decoction would be further studied through regulation of intestinal flora and improving liver insulin resistance.

关 键 词：2型糖尿病 肠热肝寒 连梅肉桂方 肠—肝轴 

分 类 号：R259[医药卫生—中西医结合]