白细胞介素-6在腹膜透析相关并发症中的作用研究进展  

Research advances of interleukin-6 in peritoneal dialysis-related complications

作　　者：杨凡 包宇实[1] Yang Fan;Bao Yu-shi(Department of Nephrology,First Affiliated Hospital,Harbin Medical University,Harbin 150000,China)

机构地区：[1]哈尔滨医科大学附属第一医院肾脏内科,150000

出　　处：《临床肾脏病杂志》2021年第6期512-515,共4页Journal Of Clinical Nephrology

基　　金：黑龙江省卫生健康委科研课题(2019-017)。

摘　　要：腹膜透析(peritoneal dialysis,PD)是终末期肾脏病患者的有效肾脏替代治疗方式,PD相关并发症是限制PD进行的重要原因。白细胞介素-6(interleukin-6,IL-6)在PD相关并发症的多种病理生理过程中起重要作用。本文主要综述IL-6在腹膜透析相关性腹膜炎(peritoneal dialysis-associated peritonitis,PDAP)、腹膜纤维化、心血管事件等PD常见并发症中研究进展,归纳总结IL-6与PD相关并发症之间的联系。Peritoneal dialysis(PD)is an effective renal replacement therapy for patients with end-stage renal disease and peritoneal dialysis-related complications have restrict the development of PD.Interleukin-6 plays an important role in pathophysiological processes of peritoneal dialysis-related complications.This review summarized the latest researches of IL-6 in peritoneal dialysis-associated peritonitis,peritoneal fibrosis and cardiovascular events and elucidated the relationship between IL-6 and peritoneal dialysis-related complications.

关 键 词：白细胞介素-6 腹膜透析相关性腹膜炎 腹膜纤维化 免疫炎症 上皮-间充质转化 

分 类 号：R692.5[医药卫生—泌尿科学]