EBUS-TBNA活检针的研究进展  

Research progress of biopsy needle in EBUS-TBNA

作　　者：蒋新成(综述) 李长毅(审校)[2] JIANG Xincheng;LI Changyi(Graduate School,Chongqing Medical University,Chongqing 400016,China;Department of Respiratory Medicine,Second Affiliated Hospital of Chongqing Medical University,Chongqing 400010,China)

机构地区：[1]重庆医科大学研究生院,400016 [2]重庆医科大学附属第二医院呼吸内科,400010

出　　处：《重庆医学》2021年第12期2137-2142,共6页Chongqing medicine

基　　金：重庆市卫生计生委医学高端后备人才资助项目(2017HBRC006)。

摘　　要：超声内镜引导下经支气管针吸活检(EBUS-TBNA)已经成为肺癌纵隔分期的一线检查方式,并广泛应用于其他纵隔疾病的诊断中。近年来关于EBUS-TBNA的程序研究逐渐开展,包含麻醉方式选择、吸力大小、是否使用针芯、淋巴结超声特征、快速细胞学应用、活检针等多个方面。活检针作为EBUS-TBNA程序中重要的一环,对其诊断效能有着极大影响。为获取最大诊断效能及解决更多组织需求量等诸多问题,多种活检针被引入EBUS-TBNA中。不同型号活检针的EBUS-TBNA诊断率有一定差异,在亚组疾病中的差异可能更加明显。不同型号活检针所获得的EBUS-TBNA样本均可用于分子、基因及PD-L1检测,但是否存在差异尚不明确。Endobronchial ultrasound-guided transbronchial needle aspiration(EBUS-TBNA)has become the first-line diagnostic method for lung cancer mediastinal staging and is widely used in the diagnosis of other mediastium diseases.In recent years,the research of EBUS-TBNA program has been carried out gradually,including the multiple aspects of anesthesia mode selection,suction size,whether use of inner-stylet,ultrasonographic features of lymph nodes,application of rapid cytology,and biopsy needle.As an important link of EBUS-TBNA program,the biopsy needle has great influence on its diagnostic efficiency.In order to obtain the maximum diagnostic efficiency and solve many problems such as more tissue requirements,various types of biopsy needles were introduced into EBUS-TBNA.The diagnostic rate of EBUS-TBNA under different types of biopsy needles is different to some extent,and the difference may be more obvious in subgroup diseases.The EBUS-TBNA samples obtained by different types of biopsy needles can be used for molecular,genetic and PD-L1 detection,but whether there is a difference is unclear.

关 键 词：支气管镜检查 活组织检查 针吸 超声检查 多普勒 综述 

分 类 号：R768.1[医药卫生—耳鼻咽喉科]