肝硬化患者抑郁情况及影响因素分析  

Analysis of depression and influencing factors in patients with liver cirrhosis

作　　者：邬菊英 陈海平 张红梅 WU Juying;CHEN Haiping;ZHANG Hongmei(Department of Integrated Chinese and Western Medicine,Xixi Hospital of Hangzhou,Hangzhou310023,China;Department of Traditional Chinese Medicine,Xixi Hospital of Hangzhou,Hangzhou310023,China)

机构地区：[1]杭州市西溪医院中西医结合科,浙江杭州310023 [2]杭州市西溪医院中医科,浙江杭州310023

出　　处：《中国现代医生》2021年第15期9-12,共4页China Modern Doctor

基　　金：浙江省中医药科技计划项目(2020ZB197)。

摘　　要：目的探讨肝硬化患者抑郁情况及影响因素分析。方法选择2019年1月至2020年1月在我院诊治的肝硬化患者48例为研究对象。采用HAMD-24量表对患者的抑郁情况进行评价,统计>20分的例数。记录患者的一般资料、临床资料以及肝硬化知信行水平。单因素及多因素分析影响肝硬化患者抑郁水平的相关因素。结果①11例≤20分的48例患者为对照组,37例>20分的患者为研究组。②大专及以上文化程度,病程>5年,有并发症,Child分级C级的患者抑郁得分研究组的比例更高,差异有统计学意义(P<0.05);研究组患者知信行得分显著低于对照组的患者,差异有统计学意义(P<0.05)。③多因素分析结果显示,文化程度高、病程长、有并发症、Child分级高是肝硬化患者抑郁的危险因素,而知信行水平高是保护因素(P<0.05)。④肝硬化患者抑郁程度与Child分级呈显著正相关性(r=0.836,P<0.05)。结论大部分肝硬化患者存在不同程度的抑郁情况。患者的学历、病程、是否合并并发症、Child分级、肝硬化知信行水平均影响其抑郁情况。临床工作中应根据患者的具体情况进行相对应的健康教育,尤其具有高风险的患者,以提高患者的知信行水平,缓解患者的抑郁情绪,提高生活质量。Objective To analyze the depression and influencing factors in patients with liver cirrhosis.Methods Forty-eight patients with liver cirrhosis treated in our hospital from January 2019 to January 2020 were selected as research subjects.HAMD-24 scale was used to evaluate the depression of patients,and the number of patients with score>20 was counted.The general information,the clinical information,and the level of the knowledge,attitude and practice of patients towards liver cirrhosis were recorded.Univariate analysis and multivariate analysis were used to analyze the relevant factors of depression in patients with liver cirrhosis.Results①Among the 48 patients,11 patients with score≤20 were divided into the control group,and 37 patients with score>20 were divided into the research group.②In patients with college and above education degree,the course of disease>5 years,complications,and Child grade C,the proportion of depression score in the study group was higher than that in the control group,with statically significant difference(P<0.05).③Multivariate analysis showed that high education degree,long course of disease,with complications and high Child grade were risk factors for depression in patients with liver cirrhosis,while high level of knowledge,attitude and practice was a protective factor(P<0.05).④There was a significant positive correlation between the degree of depression and Child grade(r=0.836,P<0.05).Conclusion Most patients with liver cirrhosis have different degrees of depression.Education background,course of disease,complications,Child grade,level of knowledge,attitude and practice towards liver cirrhosis all influence the depression.In clinical work,corresponding health education should be carried out according to the specific situation of patients,especially for patients with high risk,so as to improve the level of knowledge,attitude and practice of patients,alleviate the depression of patients,and improve the quality of life.

关 键 词：肝硬化 抑郁 CHILD分级 知信行水平 影响因素 

分 类 号：R192[医药卫生—卫生事业管理]