检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:刘如如[1,2] 颜虹 赵亚玲 李强 王欣 付晗[1] 王飞[1] 陈晨[1] 李文浩[1] 党少农 LIU Ruru;YAN Hong;ZHAO Yaling;LI Qiang;WANG Xin;FU Han;WANG Fei;CHEN Chen;LI Wenhao;DANG Shaonong(Department of Disinfection and Infection Control, Xi’an Center for Disease Control and Prevention, Xi’an 710054;Department of Epidemiology and Biostatistics, School of Public Health of Xi’an Jiaotong University Health Science Center, Xi’an 710061, China)
机构地区:[1]西安市疾病预防控制中心消毒与感染控制科,陕西西安710054 [2]西安交通大学医学部公共卫生学院流行病学与卫生统计系,陕西西安710061
出 处:《西安交通大学学报(医学版)》2021年第4期617-622,共6页Journal of Xi’an Jiaotong University(Medical Sciences)
基 金:国家自然科学基金资助重点项目(No.81230016);美国中华医学基金会(No.08-925)。
摘 要:目的评价陕西汉中农村居民膳食总脂肪及脂肪酸摄入量与高血压患病风险的关系。方法采用横断面研究,利用半定量食物频率问卷调查陕西汉中地区18~80岁农村居民的膳食情况。使用log-binomial和限制性立方样条估计单不饱和脂肪酸、多不饱和脂肪酸和饱和脂肪酸3种脂肪酸和总脂肪摄入量与高血压的关联及剂量-反应关系。结果共调查2241人,其中男性774人,女性1467。调查人群单不饱和脂肪酸摄入量占总脂肪51.9%,多不饱和脂肪酸和饱和脂肪酸共占48.1%;男性总脂肪和3种脂肪酸摄入量均明显高于女性(P<0.001)。女性人群中,调整能量、部分社会人口学因素和生活方式后,Q1组为参照,单不饱和脂肪酸Q4组人群高血压患病风险明显降低(PR:0.71,95%CI:0.54~0.92;趋势检验P=0.022)。限制性立方样条分析结果显示,女性人群单不饱和脂肪酸摄入量与高血压患病风险呈非线性剂量-反应关系(非线性检验,P<0.01)。总脂肪、饱和脂肪酸和多不饱和脂肪酸与高血压患病风险无统计学关联。结论女性人群中,增加单不饱和脂肪酸的摄入可能在降低高血压患病风险方面具有积极作用,需要进一步研究验证因果推断和拐点的合理性。Objective To evaluate the associations of total fat and fatty acid consumption with the risk of hypertension among rural residents in Hanzhong,Shaanxi Province.Methods A cross-sectional survey on dietary status with a semi-quantitative food frequency questionnaire was conducted among rural residents aged between 18 and 80 years old in Hanzhong of Shaanxi.Multivariate log-binomial regression models and restricted cubic spline were used to explore the associations of dietary total fat,saturated fatty acid,polyunsaturated fatty acid and monounsaturated fatty acids with hypertension and as well as association between dose and response.Results A total of 2241 individuals were included,with 774 males and 1467 females.Monounsaturated fatty acid accounted for 51.9%of total dietary fat intake,while the other two fatty acids for 48.1%.The intake of dietary fat and any fatty acid in men was significantly in men higher than in women(P<0.001).Results of multivariable log-binomial regression indicated that after adjustment of energy,socio-demographic and lifestyles,the risk of hypertension reduced significantly in Q4 group,compared with that in Q1(PR:0.71,95%CI:0.54-0.92;P-trend:0.022)infemales.A nonlinear dose-response relationship between monounsaturated fatty acids and hypertension was detected by restricted cubic spline in women(Pnon-linear<0.01).No association was observed of total fat,saturated fatty acid and polyunsaturated fatty acid with hypertension regardless of the gender.Conclusion In women,increased consumption of monounsaturated fats might play a positive role in reducing the risk of hypertension.Further research is warranted to verify the rationality of causal inference and break-point.
分 类 号:R173[医药卫生—妇幼卫生保健]
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.117