紫外分光光度法测定盐酸赛庚啶片含量的测量不确定度分析  

Measurement Uncertainty in the Content Determination of Cyproheptadine Hydroch Tablets by UV

作　　者：骆海春 LUO Haichun(Beihai food and drug Inspection Institute,Beihai 536000,China)

机构地区：[1]北海市食品药品检验所,北京536000

出　　处：《生物化工》2021年第3期114-116,共3页Biological Chemical Engineering

摘　　要：目的:对紫外分光光度法测定盐酸赛庚啶片含量测定不确定度进行分析和评价。方法:建立紫外分光光度法测定盐酸赛庚啶片含量的数学模型,分析测量不确定度的来源并对各分量实施量化分析与评估,对合成标准不确定度进行测量,获取扩展测量的不确定度报告。结果:紫外分光光度法对盐酸赛庚啶片含量的扩展测量不确定度为0.6%,测量结果标示为(99.6±0.6)%,k=2。结论:分析产生不确定度的主要来源,为有效控制该含量测定的准确性提供可靠的理论依据。Objective:To evaluate the measurement uncertainty in the determination of cyproheptadine hydroch Tablets by UV.Methods:The mathematical model of content determination by UV was established and the uncertainty sources were analyzed.Each active component of uncertainty was calculated,and the expanded uncertainty was obtained.Results:The expanded uncertainty for the UV determination of cyproheptadine hydroch Tablets was 0.6%,and the content determination result was(99.6±0.6)%,k=2.Conclusion:The main sources of uncertainty are analyzed,which can provide reliable theoretical basis for the effective control of the method.

关 键 词：盐酸赛庚啶片 含量测定 紫外分光光光度法 不确定分析 

分 类 号：R927[医药卫生—药学]