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作 者:郭丽娜 GUO Lina(Department of Pediatric Neurology,Shengjing Hospital Affiliated to China Medical University,Liaoning Province,Shenyang 110000,China)
机构地区:[1]中国医科大学附属盛京医院小儿神经内科,辽宁沈阳110000
出 处:《中国中医药现代远程教育》2021年第11期135-137,共3页Chinese Medicine Modern Distance Education of China
摘 要:目的探究中药穴位贴敷、按摩联合西药治疗热性惊厥患儿的临床效果。方法选取2018年12月—2019年12月中国医科大学附属盛京医院儿科收治的72例热性惊厥患儿,随机分为试验组和对照组,每组36例。对照组给予地西泮静脉推注,试验组在对照组的基础上予以穴位贴敷联合按摩治疗,2组治疗时间均为14 d。比较2组患儿的治疗总有效率、免疫功能相关指标、不良反应发生情况及复发率。结果试验组患儿的治疗总有效率为91.67%(33/36),高于对照组的72.22%(26/36),差异有统计学意义(P<0.05);治疗后,试验组的血清免疫球蛋白G(IgG)、免疫球蛋白M(IgM)及免疫球蛋白A(IgA)水平低于对照组,辅助性T细胞(CD4^(+))、CD4^(+)/细胞毒性T细胞(CD8^(+))水平高于对照组,差异均有统计学意义(P<0.05);2组的不良反应总发生率比较,差异无统计学意义(P>0.05);试验组的复发率为5.56%(2/36),低于对照组的30.56%(11/36),差异有统计学意义(P<0.05)。结论中药穴位贴敷、按摩联合地西泮静脉推注治疗小儿热性惊厥临床疗效确切,可提高机体免疫功能,降低复发率,值得临床应用推广。Objective To explore the clinical effect of acupoint application and massage combined with western medicine in the treatment of febrile convulsion in children.Methods A total of 72 children with febrile convulsion who were admitted to the Department of Pediatrics of Shengjing Hospital Affiliated to China Medical University from December 2018 to December 2019 were selected.They were randomly divided into experimental group and control group,with 36 cases in each.The control group was given diazepam intravenous injection,and the experimental group was given acupoint massage combined with acupoint application on the basis of the control group.The treatment time of both groups was 14 days.The clinical efficacy,immune function,adverse reactions and recurrence rate were compared between the two groups.Results The total effective rate in experimental group was 91.67%(33/36),which was higher than that in control group(72.22%,26/36),and the difference was statistically significant(P<0.05).After treatment,the serum levels of immunoglobulin G(IgG),immunoglobulin M(IgM)and immunoglobulin A(IgA)in experimental group were lower than those in control group,and the levels of helper T cells(CD4^(+))and CD4^(+)/cytotoxic T cells(CD8^(+))in experimental group were higher than those in control group,with statistical significance(P<0.05).There was no significant difference in the total incidence of ADR between the two groups(P Bb00.05).The recurrence rate of experimental group was 5.56%(2/36),which was lower than that of control group(30.56%,11/36),and the difference was statistically significant(P<0.05).Conclusion Acupoint application and massage combined with diazepam intravenous injection in the treatment of febrile convulsion in children has definite clinical efficacy,which can improve the immune function of the body,reduce the recurrence rate,and is worthy of clinical application and promotion.
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