颈部淋巴结转移癌超声影像特点及其与细胞核增殖相关抗原表达的关系  

Ultrasonographic features of cervical lymph node metastasis and their relationship with the expression of cell proliferation-associated nuclear antigen

作　　者：郭美金[1] 姚向平 陈华丽 Guo Meijin;Yao Xiangping;Chen Huali(Department of Ultrasound,Zhejiang Quhua Hospital,Quzhou 324004,Zhejiang Province,China)

机构地区：[1]浙江衢化医院超声科,衢州324004

出　　处：《中国基层医药》2021年第6期835-838,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：浙江省衢州市科技计划项目(2018134)。

摘　　要：目的:观察颈部淋巴结转移癌的超声影像特点,并分析其与细胞核增殖相关抗原(Ki-67)表达的关系。方法:回顾性分析浙江衢化医院2017年6月至2019年7月收治的颈部淋巴结转移癌患者92例的临床资料,观察其超声影像特点和Ki-67表达情况,分析两者的相关性。结果:92例患者中经病理检查确诊158枚转移淋巴结,其主要的超声影像特点为长短径比<2有119枚(75.32%)、门部高回声消失127枚(80.38%),点状回声高回声108枚(68.35%),囊性变57枚(36.08%)、周边血流信号为混合型124枚(78.48%)、淋巴结微钙化123枚(77.85%);其中长短径比<2、点状回声高回声、周边血流信号为混合型与Ki-67高表达有相关性(χ^(2)长短径比=24.252,χ^(2)点状回声高回声=15.732,χ^(2)混合型周边血流信号=17.033,均P<0.05)。结论:颈部淋巴结转移癌的超声影像征象长短径比<2、点状回声高回声、周边血流信号为混合型与Ki-67高表达有相关性。Objective To observe the ultrasonographic features of cervical lymph node metastasis and analyze their relationship with the expression of cell proliferation-associated nuclear antigen(Ki-67).Methods The clinical data of 92 patients with cervical lymph node metastasis who received treatment in Zhejiang Quhua Hospital,China between June 2017 and July 2019 were retrospectively analyzed.The correlation between ultrasonographic features of cervical lymph node metastasis and Ki-67 expression was analyzed.Results Among the 92 patients,158 metastatic lymph nodes were confirmed by pathological examination.The main ultrasonic imaging features were the length ratio of long diameter to short diameter<2 in 119(75.32%)lymph nodes,disappearance of portal hyperechoic signal in 127(80.38%)lymph nodes,punctate hyperechoic signal in 108(68.35%)lymph nodes,cystic degeneration in 57(36.08%)lymph nodes,mixed types of peripheral blood flow signal in 124(78.48%)lymph nodes,microcalcification in 123(77.85%)lymph nodes.The length ratio of long diameter to short diameter<2,punctate hyperechoic signal and mixed types of peripheral blood flow signal were correlated with high expression of Ki-67(χ^(2)=24.252,15.732,17.033,all P<0.05).Conclusion High expression of Ki-67 is correlated with the length ratio of long diameter to short diameter<2,punctate hyperechoic signal and mixed types of peripheral blood flow signal in cervical lymph node metastasis.

关 键 词：肿瘤转移 淋巴转移 超声检查 回声定位 局部血流 增殖细胞核抗原 

分 类 号：R445.1[医药卫生—影像医学与核医学] R739.91[医药卫生—诊断学]