血管超声综合评估T2DM患者颅内外动脉粥样硬化性病变的临床效果  

Observation on the clinical efficacy in comprehensive evaluation of intracranial and extracranialatherosclerosis lesions in patients with T2DM by vascular ultrasonography

作　　者：周勤鹏 何光智 杨晓丽 徐锡虎 姚锦天 欧柱平 ZHOU Qinpeng;HE Guangzhi;YANG Xiaoli;XU Xihu;YAO Jintian;OU Zhuping(Department of Ultrasonography,Shenzhen Hospital(Guangming Branch)of University of Chinese Academy of Sciences,Guangdong,Shenzhen 518106,China;Department of Ultrasonography,Fuyong People's Hospital in Baoan District of Shenzhen City,Guangdong,Shenzhen 518103,China)

机构地区：[1]中国科学院大学深圳医院(光明)超声科,广东深圳518106 [2]深圳市宝安区福永人民医院超声科,广东深圳518103

出　　处：《中国医药科学》2021年第11期162-165,共4页China Medicine And Pharmacy

基　　金：广东省深圳市宝安区医疗卫生基础研究项目(2020JD410)。

摘　　要：目的观察血管超声综合评估2型糖尿病(T2DM)患者颅内外动脉粥样硬化性病变的临床效果分析。方法选择我院2018年7月至2020年9月期间收治的T2DM患者117例设置为观察组,另选取同期的非T2DM患者117例为对照组,行血管超声检查以评估颅内外动脉血管(颅外动脉指颈总动脉)情况,以数字减影血管造影(DSA)结果为金标准,比较血管超声IMT增厚、粥样斑块、血管狭窄率,明确颅内外动脉狭窄发生情况,分析诊断一致性。结果检查结果显示,观察组颈动脉内中膜厚度(CIMT)增厚、粥样斑块、血管狭窄率均高于对照组,差异有统计学意义(P<0.05)。观察组颅内动脉狭窄发生率明显高于颅外颈部动脉狭窄发生率,差异有统计学意义(P<0.05)。而对照组颅内与颈部动脉狭窄发生率比较,差异无统计学意义(P>0.05)。两组患者颅内、颈部动脉狭窄发生率比较,差异无统计学意义(P>0.05)。两组患者中发生重度狭窄或闭塞者6例,行DSA检查后6例明确诊断,诊断准确率100%。结论在T2DM患者颅内外动脉粥样硬化性病变的综合评估中,应用血管超声综合评估可有效帮助临床作为辅助的判断结果,指导临床治疗有着重要的意义。Objective To observe the clinical efficacy in comprehensive evaluation of intracranial and extracranial atherosclerosis lesions in patients with type 2 diabetes mellitus(T2DM)by vascular ultrasonography.Methods Patients with T2DM admitted to our hospital from July 2018 to September 2020 were selected as the observation group(n=117),and those without T2DM in the same period were selected as the control group(n=117).Vascular ultrasonography was performed to evaluate the intracranial and extracranial arteries(extracranial arteries refer to the common carotid arteries).With the results of digital subtraction angiography(DSA)as the gold standard,IMT thickening,atherosclerosis plaque and vascular stenosis rates of vascular ultrasonography were compared to confirm the occurrence of intracranial and extracranial arteries stenosis and analyze the consistency of diagnoses.Results The results proved that the carotid intima-media thickness(CIMT)thickening,atherosclerosis plaque and vascular stenosis rates in the observation group were all higher than those in the control group,with statistically significant differences(P<0.05).The incidence of intracranial artery stenosis in the observation group was significantly higher than that of extracranial carotid artery stenosis,with statistically significant difference(P<0.05).However,there was no statistically significant difference in the incidence of intracranial and cervical artery stenosis in the control group(P>0.05).Meanwhile,there were no statistically significant differences in the incidence of intracranial and cervical artery stenosis between the two groups of patients(P>0.05).There were 6 cases of severe stenosis or occlusion in the two groups,and 6 cases were definitely diagnosed after DSA examination,in which the diagnostic accuracy rate was 100%.Conclusion In the comprehensive evaluation of intracranial and extracranial atherosclerosis lesions in patients with T2DM,the application of vascular ultrasonography comprehensive evaluation can effectively help clinical judgme

关 键 词：血管超声综合评估 T2DM患者 颅内外 动脉粥样硬化性病变 

分 类 号：R445.1[医药卫生—影像医学与核医学]