米索前列醇联合超导可视无痛人流术在合并高危人流因素的初孕妇中的疗效观察  

Efficacy of misoprostol combined with superconducting visual painless induced abortion in first-time pregnant women with high-risk factors of abortion

作　　者：彭荣芳 谢伟琼 解绪红 严志强 PENG Rong-fang;XIE Wei-qiong;XIE Xu-hong(Department of Gynecology and Obstetrics,Foshan Gaoming Hospital Affiliated to Guangdong Medical University,Foshan 528500,China)

机构地区：[1]广东医科大学附属佛山高明医院妇产科,528500

出　　处：《中国实用医药》2021年第18期120-122,共3页China Practical Medicine

基　　金：佛山市卫计局十三五医学重点专科建设项目资助项目(项目编号:FSZDZK135058)。

摘　　要：目的探讨米索前列醇联合超导可视无痛人工流产(人流)术在合并高危人流因素的初孕妇中的临床疗效。方法200例合并高危人流因素的初孕妇,根据手术方式不同分为观察组和对照组,各100例。观察组行米索前列醇联合超导可视无痛人流术,对照组行普通无痛人流术。分析患者的高危人流因素构成情况,比较两组手术相关情况。结果200例患者中,年龄≤20岁者33例,子宫极度倾屈者61例,合并子宫肌瘤者45例,带器妊娠者25例,宫内有纵隔者4例,宫颈暴露困难者28例,生殖道畸形4例,其中子宫极度倾屈、合并子宫肌瘤、年龄≤20岁的占比分别为30.5%、22.5%、16.5%,均名列前3位。观察组宫颈松弛有效率94%显著高于对照组的20%,手术时间(3.19±1.34)min、术中出血量(8.12±2.81)ml显著少于对照组的(5.72±2.45)min、(12.90±4.17)ml,差异均有统计学意义(P<0.05)。观察组人流并发症发生率0显著低于对照组12%,差异均有统计学意义(χ^(2)=12.766,P=0.000<0.05)。结论在合并高危人流因素的初孕妇的治疗中,米索前列醇联合超导可视无痛人流术较普通无痛人流术更安全有效,对子宫的伤害更小,值得临床推广。Objective To discuss the clinical efficacy of misoprostol combined with superconducting visual painless induced abortion in first-time pregnant women with high-risk factors of abortion.Methods A total of 200 first-time pregnant women with high-risk factors of abortion were divided into observation group and control group according to different surgical methods,with 100 cases in each group.The observation group was treated with misoprostol combined with superconducting visual painless induced abortion,and the control group was treated with ordinary painless induced abortion.The composition of high-risk factors of abortion was analyzed,and the surgical-related conditions of the two groups were compared.Results Among the 200 patients,33 patients with age≤20 years old,61 cases with extreme uterine flexion,45 cases with uterine myoma,25 cases with pregnancy with device,4 cases with mediastinum in utero,28 cases with cervical exposure difficulties and 4 cases with genital malformations,among which the proportion of extreme uterine flexion,hysteromyoma and age≤20 years were 30.5%,22.5%and 16.5%,respectively,all ranked the top 3.The effective rate of cervical relaxation 94%of the observation group was significantly higher than 20%of the control group,and operation time(3.19±1.34)min and intraoperative blood loss(8.12±2.81)ml were significantly less than(5.72±2.45)min and(12.90±4.17)ml of the control group.All the difference was statistically significant(P<0.05).The incidence of complications 0 of the observation group was significantly lower than 12%of the control group,and the difference was statistically significant(χ^(2)=12.766,P=0.000<0.05).Conclusion For first-time pregnant women with high-risk factors of abortion,combination of misoprostol and superconducting visual painless induced abortion is safer and more effective than ordinary painless induced abortion,and has less harm to uterus,which is worthy of clinical promotion.

关 键 词：米索前列醇 超导可视无痛人流术 初孕妇 高危人流因素 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]