高血压高脂血症患者血清TC、TG水平及WBC的相关性及其对预后评估的价值  

Correlation of serum TC,TG and WBC in patients with hypertension and hyperlipidemia and its prognostic value

作　　者：成明 李慧[1] CHENG Ming;LI Hui(Health Management Center,the First People's Hospital of Lianyungang,Lianyungang 222000,Jiangsu,China)

机构地区：[1]连云港市第一人民医院健康管理中心,江苏连云港222000

出　　处：《川北医学院学报》2021年第6期798-801,共4页Journal of North Sichuan Medical College

摘　　要：目的:探究高血压高脂血症患者血清总胆固醇(TC)、甘油三酯(TG)水平及白细胞计数(WBC)的相关性及其对预后评估的价值。方法:选择100名体检健康者、163例单纯高血压、182例单纯高脂血症和173例高血压合并高脂血症者为研究对象,并分别设为健康组、对照1组、对照2组和研究组,研究组再根据随访结果分为预后良好组(n=142)和预后不良组(n=31);比较四组对象及研究组不同预后患者血清TC、TG水平及WBC,分析血清TC、TG及WBC的相关性及其对患者预后评估的价值。结果:四组研究对象血清TC、TG水平及WBC比较,差异有统计学意义(P<0.05),且研究组>对照2组>对照1组>健康组(P<0.05);预后不良组患者TC、TG及WBC高于预后良好组(P<0.05)。相关性分析显示,TC与TG、WBC和TG与WBC呈正相关(r=0.613、0.537、0.716,P<0.05)。ROC曲线分析显示,TC、TG、WBC单独及三者联合评估患者预后的AUC值分别为0.716、0.751、0.608和0.841。结论:高血压高脂血症患者血清TC、TG及WBC与患者病情变化关系密切,对患者预后评估有一定价值。Objective:To explore the correlation of serum total cholesterol(TC),triglyceride(TG)and white blood cell count(WBC)in patients with hypertension and hyperlipidemia and its prognostic value.Methods:100 healthy individuals(healthy group),163 patients with simple hypertension(control group 1),182 patients with simple hyperlipidemia(control group 2),and 173 patients with hypertension and hyperlipidemia(study group)were enrolled in the study.According to the follow-up results,the study group was further divided into good prognosis group(n=142)and poor prognosis group(n=31).The levels of serum TC,TG and WBC were compared among the four groups and the patients with different prognosis in the study group.The correlation of serum TC,TG and WBC and the value of prognosis evaluation were analyzed.Results:There were significant differences in serum TC,TG and WBC among the four groups(P<0.05).And the study group>control group 2>control group 1>healthy group(P<0.05).TC,TG and WBC in poor prognosis group were higher than those in good prognosis group(P<0.05).The correlation analysis showed that TC was positively correlated with TG,WBC and TG was positively correlated with WBC(r=0.613,0.537,0.716 P<0.05).ROC curve analysis showed that the AUC values of TC,TG,WBC alone or combined were 0.716,0.751,0.608,and 0.841,respectively.Conclusion:The serum TC,TG and WBC of patients with hypertension and hyperlipidemia are closely related to the changes of the patient's condition,which has a certain value for the prognosis evaluation of patients.

关 键 词：高血压 高脂血症 血清脂类 白细胞数 

分 类 号：R589.2[医药卫生—内分泌]