反-4-氯-β-硝基苯乙烯的合成研究  

Study on the Synthesis of Methomyloxime

作　　者：徐健 罗先福 刘建雄 刘国文 臧阳陵 XU Jian;LUO Xian-fu;LIU Jian-xiong;LIU Guo-wen;ZANG Yang-ling(Hunan Haili Changde Pesticide Chemical Co.,Ltd.,Changde 415001,China;Hunan Research Institute of Chemical Industry,Changsha 410014,China;Hunan Province Key Laboratory for Agrochemicals,Changsha 410014,China)

机构地区：[1]湖南海利常德农药化工有限公司,湖南常德415001 [2]湖南化工研究院有限公司国家农药创制工程技术研究中心,湖南长沙410014 [3]农用化学品湖南省重点实验室,湖南长沙410014

出　　处：《精细化工中间体》2021年第2期35-37,45,共4页Fine Chemical Intermediates

基　　金：湖湘青年英才项目(2019RS2060)。

摘　　要：在惰性气氛保护下,以对氯苯甲醛为原料,在催化剂和脱水剂存在下与硝基甲烷反应,得到反-4-氯-β-硝基苯乙烯,收率达98.5%~99.8%(LC,外标法),含量达99.0%~99.9%(LC,外标法)。该方法具有成本低,反应速度快,环境友好等特点,具有工业化应用前景。Under the inert atmosphere,p-chlorobenzaldehyde was used as raw material,and the reaction liquid was treated after the reaction was completed.The yield of the reaction liquid was 98.5%~99.8%(liquid chromatography,external standard),and the purity reached 99.0%~99.9%(liquid chromatography,external standard),with low cost,fast reaction speed,friendly environment and so on.

关 键 词：对氯苯甲醛 Henry反应 硝基甲烷 

分 类 号：O626.2[理学—有机化学]