中医捏脊治疗小儿咳嗽变异性哮喘肺脾气虚证临床研究  

Clinical study of Chinese medical chiropractic for the children with cough variant asthma and qi deficiency of spleen and lung syndrome

作　　者：周春焕 张飞燕[2] 谭淑文 Zhou Chunhuan;Zhang Feiyan;Tan Shuwen(Graduate School,Guangzhou University of Traditional Chinese Medicine,Guangzhou 510405,China;Department of Paediatrics,Maoming Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine,Maoming 525000,China)

机构地区：[1]广州中医药大学研究生院,510405 [2]广州中医药大学附属茂名市中医院儿科,525000

出　　处：《国际中医中药杂志》2021年第6期558-562,共5页International Journal of Traditional Chinese Medicine

基　　金：广东省中医药局科研项目(20201396)。

摘　　要：目的评价中医捏脊治疗咳嗽变异性哮喘肺脾气虚证患儿的临床疗效。方法将符合入选标准的2017年10月-2018年10月广州中医药大学附属茂名市中医院儿科门诊60例咳嗽变异性哮喘肺脾气虚证患儿,采用随机数字表法分为2组,每组30例。对照组在常规治疗基础上口服孟鲁司特钠颗粒,观察组在对照组的基础上给予捏脊治疗。2组均连续治疗6周,随访2个月。分别于治疗前后进行中医证候评分,采用ELISA法检测血清IgA、IgG、IgM、IgE水平,观察并记录随访期间患儿的复发情况;评价临床疗效。结果观察组总有效率为86.7%(26/30)、对照组为56.7%(17/30),2组比较差异有统计学意义(χ^(2)=6.648,P=0.008)。观察组治疗后咳嗽、痰量、胸闷、舌苔、伴随症状评分及总分均低于对照组(t值分别为2.639、2.628、2.633、2.627、2.725、2.642,P值均<0.05)。治疗后,观察组血清IgA[(2.31±1.20)g/L比(1.55±0.72)g/L,t=2.635]、IgG[(11.16±3.39)g/L比(8.18±3.27)g/L,t=2.751]、IgM[(1.72±0.34)g/L比(1.27±0.36)g/L,t=2.660]水平均高于对照组(P<0.05),IgE[(51.32±32.62)g/L比(74.58±40.77)g/L,t=2.619]水平低于对照组(P<0.05)。随访期间,观察组复发率为19.2%(5/26)、对照组为70.6%(12/17),2组比较差异有统计学意义(χ^(2)=4.675,P=0.029)。结论中医捏脊可有效改善咳嗽变异性哮喘肺脾气虚证患儿的临床症状及血清免疫因子水平,降低复发率,提高临床疗效。Objective To evaluate the clinical effect of Chinese medical chiropractic in treating children with cough variant asthma syndrome(CVA)of Lung-Spleen Qi Deficiency.Methods From October 2017 to October 2018,60 CVA children with syndrome of lung-spleen qi deficiency were enrolled from pediatric outpatient department of Maoming Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Traditional Chinese Medicine,and they were randomly divided into the control group and observation group by random number table method,with 30 in each group.The control group was given montelukast sodium granules orally on the basis of conventional treatment,and the observation group was given chiropractic treatment on the basis of the control group.Both groups were treated for 6 weeks and followed up for 2 months.The TCM syndrome scores were performed before and after treatment,and the changes of serum IgA,IgG,IgM and IgE were detected by ELISA.The recurrence was observed and recorded during the follow-up period,and the clinical effect rate was evaluated.Results The total effect rates of the observation group and the control group were 86.7%(26/30)and 56.7%(17/30),respectively,with significant differences between the two groups(χ^(2)=6.648,P=0.008).After treatment,the scores of cough,sputum volume,oppression in chest,tongue coating,concomitant symptoms and total scores in the observation group were significantly lower than those in the control group(t values were 2.639,2.628,2.633,2.627,2.725,2.642,respectively,all Ps<0.05).After treatment,the IgA[(2.31±1.20)g/L vs.(1.55±0.72)g/L,t=2.635],IgG[(11.16±3.39)g/L vs.(8.18±3.27)g/L,t=2.751],IgM[(1.72±0.34)g/L vs.(1.27±0.36)g/L,t=2.660]in the observation group were significantly higher than those in the control group(P<0.05),while the IgE[(51.32±32.62)g/L vs.(74.58±40.77)g/L,t=2.619]in the observation group were significantly lower than those in the control group(P<0.05).During the follow-up,the recurrence rate was 19.2%(5/26)in the observation group and 70.6%(12

关 键 词：哮喘 咳嗽 儿童 肺脾气虚证 中医捏脊疗法 中西医结合疗法 

分 类 号：R272[医药卫生—中医儿科学]