葛根分子生药学研究进展  

Pueraria lobate advances in molecular pharmacognosy

作　　者：杨碧穗 黄秋连 谢璐欣 吴波[1] 邓可众[1] 吴志瑰[1] 朱卫丰[1] 何绍浪 黄琦 朱玉野[4] 葛菲[1] YANG Bi-sui;HUANG Qiu-lian;XIE Lu-xin;WU Bo;DENG Ke-zhong;WU Zhi-gui;ZHU Wei-feng;HE Shao-lang;HUANG Qi;ZHU Yu-ye;GE Fei(School of Pharmacy,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China;Jiangxi Institute of Red Soil,Nanchang 330046,China;Jiangxi Province Institute of Green and Ecological Pueraria,Shangrao 334000,China;Research Center of Traditional Chinese Medicine Resourcing and Minority Medicine,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China)

机构地区：[1]江西中医药大学药学院,江西南昌330004 [2]江西省红壤研究所,江西南昌330046 [3]江西绿色生态葛研究所,江西上饶334000 [4]江西中医药大学中药资源与民族药中心,江西南昌330004

出　　处：《中国中药杂志》2021年第9期2149-2157,共9页China Journal of Chinese Materia Medica

基　　金：国家重点研发计划项目(2017YFC1702901);江西中医药大学中药学一流学科科研项目(JXSYLXK-ZHYAO024);江西省重点研发计划项目(20192BBG70074);江西省自然科学基金项目(20192BAB205102);江西省农村农业厅项目(JXARS-16)。

摘　　要：分子生药学是在分子水平上研究生药的分类与鉴定、栽培与保护及有效成分生产的一门科学,分子生药学的提出让生药的研究从微观向基因水平迈进。葛根作为药食两用植物,具有很高的应用价值和经济价值,品种众多容易造成混乱且根据传统的鉴定方法不易区分鉴别,且葛根在基因水平上的研究尚浅,因此分子生药学对葛根的研究得到学者的广泛关注。该文综述了近年来分子生药学在葛根分子鉴定、转录组测序研究、葛根功能基因的克隆和合成等方面的研究,以期为进一步推动葛根及其有效成分的开发和利用提供参考。Molecular pharmacognosy is a science of classification and identification, cultivation and protection, and production of active ingredients of graduated drugs at the molecular level. The proposal of molecular pharmacognosy allows the research of crude drugs to advance from the microscopic level to the genetic level. Pueraria lobata root, as a medicinal and edible plant, has high application value and economic value. There are many varieties that are easy to cause confusion, and it is not easy to distinguish and identify according to traditional identification methods. Moreover, the research of P. lobate root at the genetic level is still relatively shallow. the study received extensive attention of scholars. This article reviews recent research on molecular identification of P. lobate, transcriptome sequencing, cloning and synthesis of functional genes of P. lobate root in recent years in order to provide references for further promoting the development and utilization of P. lobate root and its active ingredients.

关 键 词：葛根 分子生药学 基因 分子标记 

分 类 号：S567.19[农业科学—中草药栽培]