局灶性关节软骨缺损外科治疗的研究现状  

Current researches on surgical treatments of focal articular cartilage defects

作　　者：陈有荣 林霖[1] 颜昕 宋一凡 王信杰 陈则亦 范宝石 张继英[1] 余家阔[1] CHEN You-rong;LIN Lin;YAN Xin;SONG Yi-fan;WANG Xin-jie;CHEN Ze-yi;FAN Bao-shi;ZHANG Ji-ying;YU Jia-huo(Department of Sports Medicine,Peking University Third Hospital,Institute of Sports Medicine of Peking University,Beijing Key Laboratory of Sports Injuries,Beijing 100191,China;Clinical College,Weifang Medical University,Weifang 261053,China)

机构地区：[1]北京大学第三医院运动医学科,北京大学运动医学研究所,运动医学关节伤病北京市重点实验室,北京100191 [2]潍坊医学院临床医学院,山东潍坊261053

出　　处：《中国矫形外科杂志》2021年第12期1100-1104,共5页Orthopedic Journal of China

基　　金：国家自然科学基金项目(编号:51773004,81630056,51920105006);国家重点研发计划项目(编号:2016YFC1100704)。

摘　　要：局灶性关节软骨缺损在运动医学领域较为常见,通常导致关节疼痛和功能障碍,由于软骨无血管、缺乏内源性修复细胞的特点,其自愈能力有限,若不及时治疗最终将发展为骨关节炎。手术一直是临床治疗关节软骨缺损的主要手段,按照外科修复技术主要分为姑息性手术、修复性手术、重建性手术和软骨替代性手术等四大类。本文主要就近年来有关以上不同外科手段治疗局灶性软骨缺损的适应证、优势、局限性及远期疗效等方面的进展情况进行综述。Focal articular cartilage defects are common injuries in sports medicine, which usually lead to joint pain and dysfunction.Due to the characteristics of cartilage that bloodless and lack of endogenous repair cells, the cartilage has limited self-healing potential,therefore the defects will eventually lead to osteoarthritis if left untreated. Surgery has always been the main means of clinical treatment of articular cartilage defects. According to the surgical repair technology, it can be divided into four categories: palliative surgery, repair surgery, reconstruction surgery and cartilage replacement surgery. In this paper, the recent progress of indications, advantages, limitations and long-term efficacy of the abovementioned surgical methods in the treatment of focal cartilage defects are reviewed.

关 键 词：软骨缺损 外科治疗 软骨修复 组织再生 

分 类 号：R687[医药卫生—骨科学]