EpiMap: Fine-tuning integrative epigenomics maps to understand complex human regulatory genomic circuitry  

作　　者：Dave S.B.Hoon Negin Rahimzadeh Matias A.Bustos 

机构地区：[1]Department of Translational Molecular Medicine,Division of Molecular Oncology,Saint John’s Cancer Institute at Providence Saint John’s Health Center,Santa Monica,CA,USA

出　　处：《Signal Transduction and Targeted Therapy》2021年第6期1627-1629,共3页信号转导与靶向治疗（英文）

摘　　要：In a recent paper published in Nature,Boix et al.1 developed an integrated platform on epigenomic maps that represents a significant updated resource in human regulatory circuitry as related to specific organ tissues and cells,as well as specific disease traits.The EpiMap(for epigenome integration across multiple annotation projects)is a highly valuable compendium comprising 10,000 epigenomic maps across 833 biospecimens and 33 tissue categories.The distinct biospecimens expanding coverage to life development(embryonic to adult)and different sample types including complex organ tissues as well as primary cells,and established normal and tumor cell lines.The biospecimen analysis provides a comprehensive view of human genome circuitry making EpiMap a remarkable platform for epigenomic landscapes assessment to the investigator.

关 键 词：MAPS tuning Map 

分 类 号：Q78[生物学—分子生物学]