性激素检测在不孕症诊断中的应用价值  

The Application Value of Sex Hormone Detection in the Diagnosis of Infertility

作　　者：张欣 王明 刘志敏 ZHANG Xin;WANG Ming;LIU Zhimin(Department of Laboratory Medicine,Pinggu District Hospital of Traditional Chinese Medicine,Beijing,101200 China)

机构地区：[1]北京市平谷区中医医院检验科,北京101200

出　　处：《中外医疗》2021年第13期171-173,共3页China & Foreign Medical Treatment

摘　　要：目的探讨性激素检测在不孕症诊断中的临床价值。方法选取2020年1—12月北京市平谷区中医医院收治的60例不孕症患者作为不孕组,同时选取同期60名常规健康体检者作为对照组,两组均接受催乳素(PRL)、睾酮(T)、孕酮(P)、雌二醇(E2)、黄体生成素(LH)和促卵泡生成激素(FSH)等检查,并对六项性激素水平进行比较。结果不孕组患者T[(3.66±0.83)ng/mL vs(1.72±0.38)ng/mL]、LH[(12.63±3.04)ng/mL vs(8.22±2.04)ng/mL]、PRL[(8.22±2.04)ng/mL vs(17.00±3.48)ng/mL]水平显著高于对照组,差异有统计学意义(t=16.462、9.321、10.856,P<0.05),不孕组患者P[(1.18±0.32)ng/mL vs(1.42±0.35)ng/mL]、E2[(107.32±22.50)ng/mL vs(337.12±51.14)ng/mL]水平显著低于对照组,差异有统计学意义(t=3.920、31.860,P<0.05),而两组FSH[(8.77±1.66)ng/mL vs(8.33±1.22)ng/mL]水平比较差异无统计学意义(t=1.654,P>0.05)。结论不孕组女性均具有一定程度的内分泌失调,对性激素指标进行检测有助于评估患者生理和内分泌功能,可为不孕症的临床诊治提供参考意见。Objective To explore the clinical value of sex hormone detection in the diagnosis of infertility.Methods From January to December 2020,60 infertility patients admitted to Beijing Pinggu District Hospital of Traditional Chinese Medicine were selected as the infertility group.At the same time,60 peoples with routine health examination during the same period were selected as the control group.Both groups received prolactin(PRL),testosterone(T),progesterone(P),estradiol(E2),luteinizing hormone(LH)and follicle stimulating hormone(FSH)and other tests,and compared the levels of the six sex hormones.Results T[(3.66±0.83)ng/mL vs(1.72±0.38)ng/mL],LH[(12.63±3.04)ng/mL vs(8.22±2.04)ng/mL],PRL[(8.22±2.04)ng/mL vs(17.00±3.48)ng/mL]level was significantly higher than that of the control group,the difference was statistically significant(t=16.462,9.321,10.856,P<0.05),the infertility group was P[(1.18±0.32)ng/mL vs(1.42±0.35)ng/mL],E2[(107.32±22.50)ng/mL vs(337.12±51.14)ng/mL]levels were significantly lower than those of the control group,the difference was statistically significant(t=3.920,31.860,P<0.05),while the FSH[(8.77±1.66)ng/mL vs(8.33±1.22)ng/mL]level of the two groups was not significantly different(t=1.654,P>0.05).Conclusion All women in the infertility group have a certain degree of endocrine disorders.The detection of sex hormone indicators is helpful to assess the physiological and endocrine functions of patients,and can provide reference opinions for the clinical diagnosis and treatment of infertility.

关 键 词：不孕症 催乳素 睾酮 孕酮 雌二醇 黄体生成素 促卵泡生成激素 

分 类 号：R711[医药卫生—妇产科学]