孟鲁司特联合辅舒酮对哮喘患者临床疗效及肺功能的影响  

Impacts of montelukast combined with flixotide on clinical efficacy and pulmonary function in asthma patients

作　　者：邓镜业[1] 张凤梨 DENG Jingye;ZHANG Fengli(Department of Pediatric Internal Medicine,Jiangmen Central Hospital,Guangdong,Jiangmen 529000,China;Department of Neurology,Jiangmen Central Hospital,Guangdong,Jiangmen 529000,China)

机构地区：[1]广东省江门市中心医院儿内科,广东江门529000 [2]广东省江门市中心医院神经内科,广东江门529000

出　　处：《中国医药科学》2021年第12期58-60,共3页China Medicine And Pharmacy

摘　　要：目的探讨孟鲁司特联合辅舒酮对哮喘患者临床疗效及肺功能的影响。方法选取2018年12月至2019年12月因哮喘来我院接受治疗的96例患儿为研究对象,随机设为研究组与对照组。对照组采用辅舒酮治疗,研究组采用辅舒酮与孟鲁司特联合治疗,比较两组疗效,症状缓解时间以及治疗前后的肺功能指标。结果研究组治疗总有效率高于对照组(P<0.05);研究组各项症状改善时间均少于对照组(P<0.05);研究组治疗后的第一秒用力呼气量(FEV_(1))、最大呼气流速(PEF)及用力肺活量(FVC)指标均高于对照组(P<0.05)。结论对哮喘患者采用孟鲁司特与辅舒酮联合治疗,其效果较好,有助于缩短患者症状缓解时间,改善其肺功能指标,利于推广应用。Objective To investigate the impacts of montelukast combined with flixotide on clinical efficacy and pulmonary function in asthma patients.Methods A total of 96 children with asthma admitted to and treated in our hospital from December 2018 to December 2019 were selected as the research objects,and they were randomly divided into the study group and the control group.The control group was treated with flixotide,while the study group was treated with flixotide combined with montelukast.The therapeutic efficacy,symptom relief time and pulmonary function indices before and after treatment were compared between the two groups.Results The total effective rate of the study group was higher than that of the control group(P<0.05).The improvement time of each symptom in the study group was all shorter than that in the control group(P<0.05).After treatment,the indices of the first second forced expiratory volume(FEV_(1)),peak expiratory flow rate(PEF)and forced vital capacity(FVC)of the study group were all higher than those of the control group(P<0.05).Conclusion The combined treatment of montelukast and flixotide for asthma patients has a good efficacy,which is conducive to shortening the symptom relief time and improving the pulmonary function index.Therefore,it is good f or promotion and application.

关 键 词：孟鲁司特 辅舒酮 哮喘患者 临床症状 肺功能 

分 类 号：R725.6[医药卫生—儿科]