连续性血液滤过在重症中暑患者救治中的应用研究  

Application Study of Continuous Hemofiltration in Severe Heatstroke Treatment

作　　者：丛雪 CONG Xue(Shenyang First People's Hospital,Shenyang 110041,China)

机构地区：[1]沈阳市第一人民医院,辽宁沈阳110041

出　　处：《中国医药指南》2021年第15期36-37,40,共3页Guide of China Medicine

摘　　要：目的研究连续性血液滤过在重症中暑患者救治中的应用价值。方法选取我院2018年1月至2019年6月收治的28例重症中暑患者,按随机序列法,分为观察组和对照组,每组14例。对照组行常规治疗,观察组行连续性血液滤过,对比两组治疗前后肝肾功能、体温变化,统计救治有效率。结果两组治疗前白蛋白、丙氨酸转氨酶、血尿素氮、血肌酐以及体温接近(P>0.05);治疗后,观察组患者的白蛋白水平为(52.34±3.42)g/L、丙氨酸转氨酶水平为(48.65±2.83)μmol/L、血尿素氮水平为(8.41±0.56)mmol/L、血肌酐水平为(125.74±16.48)μmol/L、体温为(37.68±0.59)℃,对照组患者的白蛋白水平为(58.44±4.25)g/L、丙氨酸转氨酶水平为(59.21±3.40)μmol/L、血尿素氮水平为(9.21±0.74)mmol/L、血肌酐水平为(137.28±19.17)μmol/L、体温为(38.35±0.66)℃,两组差异具有统计学意义(P均<0.05,t=20.352、41.993、19.526、81.063、52.806)。观察组救治有效率为92.86%(13/14),对照组患者的救治有效率为78.57%(11/14),两组差异具有统计学意义(P<0.05,χ2=14.101)。结论在重症中暑患者的救治中,应用连续性血液滤过可提升救治有效率,改善患者病情,控制体温,改善肝脏和肾功功能水平。Objective To study the application value of continuous hemofiltration in the treatment of severe heatstroke.Methods Twenty-eight patients with severe heatstroke admitted to our hospital from January 2018 to June 2019 were randomly divided into observation group and control group,with 14 cases in each group.The control group received routine treatment,while the observation group received continuous hemofiltration.The changes of liver and kidney function and body temperature before and after treatment were compared between the two groups,and the effective rate of treatment was counted.Results Albumin,alanine aminotransferase,blood urea nitrogen,serum creatinine and body temperature in the two groups were similar before treatment(P>0.05).After treatment,the albumin level in the observation group was(52.34±3.42)g/L,the alanine aminotransferase level was(48.65±2.83)μmol/L,the blood urea nitrogen level was(8.41±0.56)mmol/L,and the serum creatinine level was(125.74±16.48)μmol/L,the body temperature was(37.68±0.59)℃.The levels of albumin,glutamic-pyruvic aminotransferase,urea nitrogen,creatinine and body temperature in the control group were(58.44±4.25)g/L,(59.21±3.40)μmol/L,(9.21±0.74)mmol/L,(137.28±19.17)μmol/L and(38.35±0.66)℃respectively.There were statistical differences between the two groups(all P<0.05,t=20.352,41.993,19.526,81.063,52.806).The effective rate of treatment in the observation group was 92.86%(13/14)and that in the control group was 78.57%(11/14).The difference between the two groups was statistically significant(P<0.05,χ2=14.101).Conclusion In the treatment of severe heatstroke patients,the application of continuous hemofiltration can improve the treatment efficiency,improve the patient's condition,control body temperature and serum inflammatory factors.

关 键 词：重症中暑 连续性血液滤过 血尿素氮 白蛋白 

分 类 号：R594.12[医药卫生—内科学]