基于支付意愿的卫生经济学评价中成本效果阈值研究系统评价  

Systematic Evaluation of Cost Effectiveness Threshold Research in Health Economics Evaluation Based on Willingness to Pay

作　　者：李环 李程洪 刘红海 黄梅香 张治国[1,2] LI Huan(School of Medicine and Health Management,Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei,430030,China)

机构地区：[1]华中科技大学同济医学院医药卫生管理学院,湖北武汉430030 [2]湖北省卫生技术评估研究中心,湖北武汉430030

出　　处：《医学与社会》2021年第7期36-41,共6页Medicine and Society

基　　金：中央高校基本科研业务费专项资金资助项目,编号为2019WKYXZX009;国家自然科学基金资助项目,编号为71273100。

摘　　要：目的:对每QALY支付意愿(Willingness to Pay per QALY,WTP/QALY)的实证研究进行系统评价,为我国今后开展此类研究提供参考。方法:检索PubMed、Embase和HTA Database数据库,搜集公开发表的每QALY支付意愿的实证研究。结果:最终纳入36项研究,测量QALY的最常用方法是视觉模拟量表,其次是EQ-5D;测量WTP的最常用方法是开放式问题,其次是投标博弈。37.14%的研究报告单一阈值,62.86%的研究报告阈值区间。分析阈值与人均GDP的比值发现,对于单一阈值研究,82.97%的比值小于2;对于阈值区间研究,78.05%的比值区间的上限值小于2。结论:应加强国内对每QALY支付意愿的实证研究,不推荐使用WHO推荐的阈值。Objective:To evaluate the empirical research on willingness to pay per QALY systematically,so as to provide a reference for future research in China.Methods:PubMed,Embase and HTA Database were searched to collect empirical research on the willingness to pay per QALY.Results:36 researches were finally included.The most commonly used method to obtain QALY was the visual analog scale,followed by EQ-5D.The most commonly used method to obtain WTP was open-ended question,followed by bidding game.37.14% of the studies reported a single threshold and 62.86% of them reported a threshold interval.By analyzing the ratio of QALY to per capita GDP,it was found that for the single threshold studies,82.97% of them had a ratio less than 2.For the threshold interval studies,the upper limit of the ratio interval in 78.05% of them was less than 2.Conclusion:Empirical research on willingness to pay per QALY in China should be strengthened.It is not recommended to use the threshold recommended by WHO.

关 键 词：质量调整生命年 成本效果阈值 支付意愿 

分 类 号：R195[医药卫生—卫生统计学]