复方芩兰口服液治疗外感风热型感冒患儿的效果  

Effects of Fufang Qinlan oral liquid in treatment of children of common cold with exogenous wind-heat syndrome

作　　者：金辉[1] JIN Hui(Emergency Department of Kunming Children’s Hospital,Kunming 650000 Yunnan,China)

机构地区：[1]昆明市儿童医院急诊科,云南昆明650000

出　　处：《中国民康医学》2021年第10期1-3,7,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:观察复方芩兰口服液治疗外感风热型感冒患儿的效果。方法:选取140例外感风热型感冒患儿作为研究对象,按照随机数字表法将其分为对照组和观察组各70例。对照组给予双黄连口服液治疗,观察组给予复方芩兰口服液治疗,比较两组临床疗效,治疗前后中医证候积分和炎性因子水平,以及不良反应发生率。结果:观察组治疗总有效率为95.71%,明显高于对照组的77.14%,差异有统计学意义(P<0.05);治疗后,观察组发热、鼻塞、咽痛/咽部红肿、流黄浊涕、汗出、头痛、咳嗽、口渴欲饮等中医证候积分均低于对照组,差异有统计学意义(P<0.05);观察组超敏C反应蛋白、肿瘤坏死因子-α和白细胞介素-6水平均低于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为4.29%,低于对照组的14.29%,差异有统计学意义(P<0.05)。结论:复方芩兰口服液治疗外感风热型感冒患儿可提高治疗总有效率,降低中医证候积分、炎性因子水平和不良反应发生率,其效果优于双黄连口服液治疗。Objective:To observe effects of Fufang Qinlan oral liquid in treatment of children of common cold with exogenous wind-heat syndrome.Methods:140 children of common cold with exogenous wind-heat syndrome were selected as the research objects,and were divided into control group and observation group according to the random number table method,70 cases in each group.The control group was treated with Shuanghuanglian oral liquid,while the observation group was treated with Fufang Qinlan oral liquid.The clinical efficacy,TCM syndrome scores before and after the treatment,the levels of inflammatory factors,and the incidence of adverse reactions were compared between the two groups.Results:The total effective rate of treatment in the observation group was 95.71%,which was significantly higher than 77.14%in the control group,and the difference was statistically significant(P<0.05).After the treatment,the scores of TCM syndromes in the observation group such as fever,nasal congestion,sore throat/redness and swelling of the throat,yellow and turbid nose,sweating,headache,cough,thirst and desiring to drink were lower than those of the control group,and the differences were statistically significant(P<0.05).The levels of hypersensitivity C-reactive protein,tumor necrosis factor-αand interleukin-6 in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,the incidence of adverse reactions in the observation group was 4.29%,which was lower than 14.29%in the control group,and the difference was statistically significant(P<0.05).Conclusions:Fufang Qinlan oral liquid in the treatment of the children of common cold with exogenous wind-heat syndrome can increase the total effective rate of treatment and reduce the TCM syndrome score,the levels of inflammatory factors and the incidence of adverse reactions.Moreover,it is superior to Shuanghuanglian oral liquid.

关 键 词：复方芩兰口服液 感冒 外感风热证 中医证候积分 炎性因子 不良反应 

分 类 号：R254.9[医药卫生—中医内科学]