AIDA研究新进展  

Research Progress on AIDA

作　　者：赵鑫 张茂森 郭慧芳 ZHAO Xin;ZHANG Mao-Sen;GUO Hui-Fang(School of public health,Xi’an Medical University,Xi’an Shaanxi 710021,China;Shaanxi Key Laboratory of Brain Disorders&School of Basic Medical Science,Xi’an Medical University,Xi’an Shaanxi 710021,China)

机构地区：[1]西安医学院公共卫生学院,陕西西安710021 [2]陕西省脑疾病防治重点实验室/西安医学院基础医学部,陕西西安710021

出　　处：《医学食疗与健康》2021年第7期197-198,共2页Medical Diet and Health

基　　金：陕西省大学生创新创业训练计划项目(编号:201825048);西安医学院大学生创新创业训练计划项目(编号:2018DC-48)。

摘　　要：体轴发育抑制因子(Axin)相互作用和背侧发育相关蛋白(AIDA)具有多种生物学活性,广泛表达于各组织的不同生长发育时段。AIDA可通过破环Axin的同二聚体化减少胚胎背侧化程度,最终影响胚胎发育过程中体轴的确定;AIDA还可以促进TAG合成相关的酶类降解以减少肠粘膜上皮细胞对脂类的吸收。AIDA is expressed in various tissues and at different growth stages,which has many biological activities.Firstly,AIDA reduces the degree of embryo dorsalization by breaking the homodimerization of Axin,and finally affects the determination of body axis during embryo development.In addition,AIDA can promote the degradation of enzymes related to TAG synthesis to reduce lipid absorption.

关 键 词：AIDA 体轴确定 三酰甘油 

分 类 号：Q74[生物学—分子生物学]