白色毛发产生对白癜风皮损复色的影响  

Effect of White Hair on the Repigmentation of Vitiligo Lesions

作　　者：陈莹莹 毕晓东[1] CHEN Yingying;BI Xiaodong(Department of Dermatological,Nanyang First People’s Hospital,Nanyang 473000,China)

机构地区：[1]南阳市第一人民医院皮肤科,河南南阳473000

出　　处：《河南医学研究》2021年第16期2913-2916,共4页Henan Medical Research

摘　　要：目的了解白癜风皮损处白色毛发的出现对皮损复色的影响。方法收集2015年3月1日至2020年3月1日于南阳市第一人民医院门诊就诊的1370例白癜风患者的资料。患者均留有皮肤镜影像结果。根据首诊时有无白色毛发将患者分为N组(无白色毛发,685例)和W组(有白色毛发,685例)。给予患者规范治疗6个月,比较不同性别、病程及亚型患者的皮损复色情况。结果W组复色率较N组低(P<0.05)。N组男性复色率与女性复色率比较,差异无统计学意义(P>0.05);W组男性复色率高于女性复色率(P<0.05);与N组比较,W组男性复色率和女性复色率均较低(P<0.05)。N组和W组进展期复色率均高于稳定期复色率(P<0.05);W组进展期和稳定期复色率均较N组低(P<0.05)。N组节段型及未定类型进展期复色率均高于稳定期(P<0.05);W组节段型、散发型及未定类型进展期复色率均高于稳定期(P<0.05)。W组进展期节段型、面肢端型及未定类型的复色率均低于N组(P<0.05);W组稳定期节段型、散发型、面肢端型及未定类型的复色率均低于N组(P<0.05)。结论白色毛发的出现可能为评价白癜风复色概率的重要指标。Objective To understand the effect of the appearance of white hair on the repigmentation of vitiligo lesions.Methods The data of 1370 patients with vitiligo who were treated in the Outpatient Department of Nanyang First People’s Hospital from March 1,2015 to March 1,2020 were collected.All patients had the results of dermatoscope images.According to the appearance of white hair in the first diagnosis,the patients were divided into group N(685 cases without white hair)and group W(685 cases with white hair).Patients were given standardized treatment for 6 months,and the repigmentation rates of patients with different gender,duration and subtypes were compared.Results The overall repigmentation rate in group W was lower than that in group N(P<0.05).There was no statistical difference in the repigmentation rate between male and female in group N(P>0.05).The repigmentation rate of male was higher than that of female in group W(P<0.05).The repigmentation rates of male and female in group W were lower than those in group N(P<0.05).In group W and group N,the repigmentation rates in the advanced stage were higher than those in the stable phase(P<0.05).The repigmentation rates in group W in the advanced stage and the stable phase were lower than those in group N(P<0.05).The repigmentation rates of the segmental and undetermined types in group N in the advanced stage were higher than those in the stable phase(P<0.05).The repigmentation rates of the segmental,sporadic and undetermined types in group W in the advanced stage were higher than those in the stable phase(P<0.05).The repigmentation rates of segmental type,facial acral type and undetermined types in group W in the advanced stage were lower than those in group N(P<0.05).The repigmentation rates of segmental type,sporadic type,facial acral type and undetermined types in group W in the stable phase were lower than those in group N(P<0.05).Conclusion The appearance of white hair may be an important indicator for the evaluation of the repigmentation chance of vitiligo.

关 键 词：白癜风 毛发 皮肤镜 复色 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]