Coinfection with malaria and intestinal parasites, and its association with anaemia in children in Cameroon  

作　　者：Anna Longdoh Njunda Shuri Ghasarah Fon Jules Clement Nguedia Assob Dickson Shey Nsagha Tayong Dizzle Bita Kwenti Tebit Emmanuel Kwenti 

机构地区：[1]Department of Medical Laboratory Sciences,University of Buea,P.B.63,Buea,Cameroon [2]Department of Public Health and Hygiene,University of Buea,P.B.63,Buea,Cameroon [3]Department of Microbiology and Parasitology,University of Buea,P.B.63,Buea,Cameroon

出　　处：《Infectious Diseases of Poverty》2015年第1期382-388,共7页贫困所致传染病（英文）

摘　　要：Background:The purpose of this study was to determine the prevalence of coinfection with malaria and intestinal parasites,as well as to determine its association with anaemia in children aged 10 years and below in Muyuka,Cameroon.Materials and methods:This was a cross-sectional study.Participants were febrile children who were admitted to the Muyuka district hospital between April and October 2012.Blood and stool samples were collected from those participants who gave consent to take part in the study.Haemoglobin concentration(Hb)and complete blood count(CBC)were performed using an automated haematology analyser(Mindray®,BC-2800).Giemsa-stained blood film was examined to detect malaria parasites,while the formol-ether concentration technique was used to detect intestinal parasitic infections(IPIs).The Pearson’s chi-square,Student’s T-test and correlation analysis were all performed as part of the statistical analyses.Results:Four hundred and eleven(411)children successfully took part in this study.The prevalence of malaria,IPIs,malaria and IPI coinfection,and anaemia observed were 98.5%,11.9%,11.9%and 44.8%,respectively.Anaemia and IPIs were significantly associated with age;anaemia was more prevalent in children under five years of age(p=0.000),whereas IPIs were more prevalent in children aged between five and 10 years(p=0.006).The parasite species isolated included Ascaris lumbricoides(36[73.5%]),Entamoeba histolytica/dispar(9[18.4%])and hookworm(4[8.2%]).The mean Hb observed was 10.64 g/dl(±1.82).A significant negative correlation was observed between malaria parasite density and Hb.There was no significant difference in the prevalence of anaemia among children infected with malaria,IPIs,or malaria and IPI coinfection,or among non-infected children.Similarly,the mean Hb did not differ among infected and non-infected children.Conclusion:This study showed that malaria and IPIs still constitute a major public health problem in the study area despite a lack of any significant association between these infect

关 键 词：MALARIA Intestinal parasites Intestinal parasitic infections COINFECTION ANAEMIA CHILDREN PREVALENCE Cameroon 

分 类 号：R53[医药卫生—内科学]