经性传播志贺菌感染的流行现状及检测方法的研究进展  

Latest progress on the epidemic status and detection methods of sexually transmitted Shigella

作　　者：周潜 韩燕 刘经纬 尹跃平 ZHOU Qian;HAN Yan;LIU Jingwei;YIN Yueping(Institute of Dermatology,Chinese Academy of Medical Sciences and Peking Union Medical College,National Center for STD Control,China CDC,Nanjing 210042,Jiangsu,China)

机构地区：[1]中国医学科学院北京协和医学院皮肤病医院/中国疾病预防控制中心性病控制中心,南京210042

出　　处：《中国艾滋病性病》2021年第6期675-676,F0003,F0004,共4页Chinese Journal of Aids & STD

基　　金：中国医学科学院医学与健康科技创新工程项目(2016-I2M-3-021);“艾滋病和病毒性肝炎等重大传染病防治”科技重大专项基金项目(2018ZX10101001-004-003);南京市国家级临床医学中心培育计划(2019060001)。

摘　　要：志贺菌是常见的革兰阴性致病菌,是细菌性痢疾的病原体。近年来,性传播已成为志贺菌重要的传播途径之一,经性传播志贺菌对抗菌药物的低敏或耐药也不断出现。本文对经性传播志贺菌感染的流行病学、耐药现状与检测方法进行了综述,比较了培养法、免疫学方法与分子检测法的原理和检测性能,为我国开展对经性传播的志贺菌感染的防治提供参考依据。Shigella is a common gram-negative bacteria and the pathogen of bacillary dysentery.In recent years,sexual transmission has become an important part of Shigella epidemiology.The low sensitivity or drug resistance of sexually transmitted Shigella is also emerging.This review explained the epidemiology,drug resistance,and detection methods of Shigella through sexual transmission.The principle and limit of detection(LOD)of culture method,immunology method,and molecular detection method were compared to provide scientific references for the prevention and control of Shigella.

关 键 词：志贺菌 性传播疾病 流行病学 检测方法 

分 类 号：R759[医药卫生—皮肤病学与性病学] R378.2[医药卫生—临床医学]