血液灌流联合常规透析对维持性血液透析伴高血压患者血压的影响  

The Effect of Hemoperfusion Combined with Conventional Dialysis on Blood Pressure in Maintenance Hemodialysis Patients with Hypertension

作　　者：周丽萍 卓金樟 ZHOU Liping;ZHUO Jinzhang(Department of Nephrology,Ningde Mindong Hospital Affiliated to Fujian Medical University,Ningde,Fujian Province,355000 China;Emergency Department,Ningde Mindong Hospital Affiliated to Fujian Medical University,Ningde,Fujian Province,355000 China)

机构地区：[1]福建医科大学附属宁德市闽东医院肾内科,福建宁德355000 [2]福建医科大学附属宁德市闽东医院急诊科,福建宁德355000

出　　处：《中外医疗》2021年第14期64-66,共3页China & Foreign Medical Treatment

摘　　要：目的探讨血液灌流联合常规透析对维持性血液透析伴高血压患者血压的影响。方法回顾性分析该院2018年12月—2019年12月收治的终末期肾病伴高血压患者95例,根据纳入及排除标准,选取73例患者纳入研究,将38例采用常规透析的患者纳入对照组,将35例采用常规透析联合血液灌流治疗的患者纳入观察组,通过回顾两组患者的资料情况,对比两组治疗后血压情况。结果治疗后对照组收缩压、舒张压未见明显改变,而观察组收缩压及舒张压随着治疗4、8、12周逐渐降低,差异有统计学意义(P<0.05)。治疗后对照组ET-1、Lep未见明显改变,而观察组ET-1、Lep随着治疗4、8、12周逐渐降低,差异有统计学意义(P<0.05)。观察组QOL评分在治疗8周后(42.38±5.31)分、12周后(48.69±3.74)分显著高于对照组的(37.46±5.24)分、(42.41±4.68)分,差异有统计学意义(t=3.982、6.299,P<0.05)。结论血液灌流联合常规透析对维持性血液透析伴高血压患者血压的控制效果较好,生活质量显著提升。Objective To investigate the effect of hemoperfusion combined with conventional dialysis on blood pressure in patients with maintenance hemodialysis with hypertension.Methods A retrospective analysis of 95 patients with end-stage renal disease and hypertension admitted to the hospital from December 2018 to December 2019.According to the inclusion and exclusion criteria,73 patients were selected into the study,and 38 patients on conventional dialysis were included in the control group,35 patients who were treated with conventional dialysis combined with hemoperfusion were included in the observation group.By reviewing the data of the two groups of patients,the blood pressure status of the two groups after treatment was compared.Results After treatment,the systolic blood pressure and diastolic blood pressure of the control group did not change significantly,while the systolic blood pressure and diastolic blood pressure of the observation group gradually decreased with the treatment for 4,8 and 12 weeks,and the difference was statistically significant(P<0.05).After treatment,the ET-1 and Lep of the control group did not change significantly,while the ET-1 and Lep of the observation group gradually decreased with the treatment for 4,8 and 12 weeks,and the difference was statistically significant(P<0.05).The QOL scores of the observation group after 8 weeks of treatment(42.38±5.31)points and 12 weeks(48.69±3.74)points were significantly higher than those of the control group(37.46±5.24)points and(42.41±4.68)points.The difference was statistically significant(t=3.982,6.299,P<0.05).Conclusion Hemoperfusion combined with conventional dialysis has a better control effect on blood pressure in patients with maintenance hemodialysis with hypertension,and the quality of life is significantly improved.

关 键 词：血液灌流 常规透析 维持性血液透析 高血压 

分 类 号：R692.5[医药卫生—泌尿科学] R544.1[医药卫生—外科学]