ACE Star模式的循证护理对非小细胞肺癌^(125)I粒子植入治疗后患者肺功能康复的影响  

Effect of evidence-based nursing in ACE Star mode on the pulmonary functional rehabilitation of patients with non-small cell lung cancer after ^(125)I seed implantation

作　　者：武建凤 霍玉青 张晓霞[1] 周静 WU Jianfeng;ZHAI Yuqing;ZHANG Xiaoxia;ZHOU Jing(Affiliated Hospital of Binzhou Medical University,Binzhou,256600,China)

机构地区：[1]滨州医学院附属医院,山东省滨州市256600

出　　处：《护理实践与研究》2021年第14期2068-2072,共5页Nursing Practice and Research

摘　　要：目的探究基于ACE Star模式的循证护理用于非小细胞肺癌^(125)I粒子植入治疗后肺功能康复的实践效果。方法选取2018年1月—2020年1月医院就诊的非小细胞肺癌行^(125)I粒子植入治疗患者98例,本院于2019年1月行循证护理,将行循证护理前后患者分别纳入对照组(n=46)和观察组(n=52)。对照组实施常规肺功能康复护理,观察组实施基于ACEStar模式的循证护理,比较两组患者术后28 d的6min步行距离、BODE指数、改良英国呼吸困难指数(mMRC)评分、呼吸功能、肺癌预后因子水平。结果观察组患者最大通气量(MVV)、FEV1/FVC、用力肺活量(FVC)、肺一氧化碳弥散量(DLCO)、6 min步行距离均高于对照组,组间比较差异具有统计学意义(P<0.05);观察组患者BODE指数、mMRC评分、血管内皮生长因子(VEGF)、血管内皮细胞生长因子受体2(VEGFR2)均低于对照组,差异具有统计学意义(P<0.05)。结论非小细胞肺癌患者行^(125)I粒子植入治疗期间行基于ACE Star模式的循证护理,能够有效改善患者肺功能,减轻呼吸困难风险,促进预后因子下调。Objective To explore the practical effects of evidence-based nursing based on the ACE Star model for pulmonary function rehabilitation after ^(125)I seed implantation treatment for non-small cell lung cancer.Methods A total of 98 patients with non-small cell lung cancer who were treated with ^(125)I seed implantation were selected from January 2018 to January 2020.The hospital performed evidence-based care in January 2019,and we included patients before and after the evidence-based care into a control group(n=46)and an observation group(n=52).The control group received routine pulmonary function rehabilitation care,and the observation group received evidence-based care based on the ACE Star model to compare the 6 min walking distance,BODE index,modified Medical Research Council dyspnea scale(mMRC)score,respiratory function,and lung cancer prognostic factor levels between the two groups at 28 days postoperatively.Results The maximal voluntary ventilation(MVV),FEV1/FVC,forced vital capacity(FVC),diffusion capacity for carbon monoxide of lung(DLCO),and 6 min walking distance in the observation group were higher than those in the control group,and the differences between the groups were statistically significant(P<0.05).The BODE index,mMRC score,vascular endothelial growth factor(VEGF),and vascular endothelial growth factor receptor 2(VEGFR2)in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Evidence-based care based on the ACE Star model during the ^(125)I seed implantation treatment of non-small cell lung cancer patients can effectively improve the patient’s pulmonary function,reduce the risk of dyspnea,and promote the down-regulation of prognostic factors.

关 键 词：非小细胞肺癌 125I植入治疗 肺功能 循证护理 康复 

分 类 号：R473.73[医药卫生—护理学]