MRI小肠 造影可评估克罗恩病活动度分级及临床活动指数  

The Correlation analysis between MRI enterography and Crohn's disease activity index on Crohn's disease activity

作　　者：郭淑栋 张贝贝 丁孝民 田春梅[3] 董立杰 陈亮[1] 姜兴岳[1] 张林[1] GUO Shudong;ZHANG Beibei;DING Xiaomin;TIAN Chunmei;DONG Lijie;CHEN Liang;JIANG Xingyue;ZHANG Lin(Department of Radiology,Binzhou Medical College Affiliated Hospital,Binzhou 256603,China;Department of Radiology,Binzhou People's Hospital,Binzhou 256600,China;Department of Pediatrics,Binzhou Medical College Affiliated Hospital,Binzhou 256603,China)

机构地区：[1]滨州医学院附属医院放射科,山东滨州256603 [2]滨州市人民医院放射科,山东滨州256600 [3]滨州医学院附属医院儿科,山东滨州256603

出　　处：《分子影像学杂志》2021年第4期618-623,共6页Journal of Molecular Imaging

基　　金：山东省自然科学基金(ZR2018LH015);山东省医药卫生科技发展计划(2017WSB30158)。

摘　　要：目的探讨MRI小肠造影(MRE)对克罗恩病活动度分级的评估及其与临床克罗恩病活动指数(CDAI)的相关性。方法对22例临床或病理确诊并经临床活动度分级的活动性克罗恩病患者行MRE检查。扫描后的图像由2名副主任及以上诊断医师对克罗恩病进行主观评分,并按其得分进行影像学活动度分级,比较评估结果与该患者临床分级结果相比较,观察其一致性。结果22例活动性克罗恩病患者均完成MRE检查,其中轻度患者7例,得分6.5±1.7分,中位数6.0分;中度患者9例,得分11.9±1.6分,中位数12.0分;重度患者6例,得分24.0±5.4分,中位得分23.5分。Spearman相关分析显示,MRE克罗恩病轻度、中度、重度与临床CDAI相关系数分别为r=0.873、0.826、0.899(P<0.05)。结论MRE与临床CDAI具有相关性,可以对活动性克罗恩病的活动度分级进行准确评估,为临床治疗提供参考。Objective To explore the correlation between magnetic resonance imaging enterography(MRE)on the classification of Crohn's disease activity and clinical Crohn's disease activity index(CDAI).Methods Twenty-two patients with active Crohn's disease diagnosed clinically or pathologically and graded by clinical activity were examined by MRE.The scanned images were scored subjectively by 2 deputy director or above diagnostic physicians,and the classification of image activity was conducted according to their scores.Then the results were compared with the clinical classification results of the patient,and the consistency was observed.Results All 22 patients with active Crohn's disease completed MRE,of which 7 were mild patients with a score of 6.5±1.7 and a median of 6.0.Nine were moderate patients with a score of 11.9±1.6.The median was 12.0 points;6 severe patients had a score of 24.0±5.4 points and the median was 23.5 points.Spearman correlation analysis was used to compare Crohn's disease activity grading criteria with clinical CDAI calculation methods.The correlations were r=0.873、0.826、0.899,respectively(P<0.05).Conclusion MRE has a significant correlation with CDAI.It can assess the activity grade of active Crohn's disease accurately and provide reference for clinical treatment.

关 键 词：MRI小肠造影 克罗恩病 活动度分级 临床活动指数 

分 类 号：R445.2[医药卫生—影像医学与核医学] R574[医药卫生—诊断学]