动态功能连接分析在脑卒中近5年的应用现状  

The application status of dynamic functional network connectivity in stroke in recent 5 years

作　　者：王宇 谭乔芮 张元 秦子玲 鲁海[1,2] 张春红 WANG Yu;TAN Qiaorui;ZHANG Yuan;QIN Ziling;LU Hai;ZHANG Chunhong(Department of Acupuncture and Moxibustion,First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300381,China;Graduate School,Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China;Department of Acupuncture and Moxibustion,Baoan Pure Traditional Chinese Medicine Treatment Hospital,Shenzhen 518000,China;National Clinical Medicine Research Center of Traditional Chinese Medicine,Tianjin 300381,China)

机构地区：[1]天津中医药大学第一附属医院针灸临床部,天津300381 [2]天津中医药大学研究生院,天津301617 [3]深圳宝安纯中医治疗医院针灸推拿康复科,广东深圳518000 [4]国家中医针灸临床医学研究中心,天津300381

出　　处：《分子影像学杂志》2021年第4期714-717,共4页Journal of Molecular Imaging

基　　金：国家重点研发计划项目-政府间国际科技创新合作重点专项(2018YFE0181700)。

摘　　要：脑卒中是一种影响脑网络的疾病,功能磁共振成像技术广泛用于研究卒中损伤后大脑的功能变化和网络重组。动态功能连接是一种新兴的分析方法,用以表征静息状态下大脑功能连接的动态特性。动态功能连接在近5年应用于脑卒中领域,主要用于探索全脑不同网络、感觉运动网络以及语言网络的功能连接属性。研究表明卒中发生后大脑网络功能连接呈现一些重复出现的密集或稀疏的连接状态并具有不同的时间变异特征,为研究脑卒中提供了新的视角,具有潜在的优势。本研究主要综述动态功能连接在脑卒中的应用现状,包括卒中后全脑网络研究、感觉运动网络研究、语言网络研究等方面。Stroke is a disease which affects brain networks.Functional magnetic resonance imaging is widely used to explore the functional changes and brain reorganization after stroke injury.Dynamic functional network connectivity is a new method to describe the dynamic characteristics of brain functional connectivity at rest stage.In recent 5 years,the application of dynamic functional network connectivity analysis in the field of stroke was mainly used to explore the functional connectivity properties of different brain networks,sensorimotor networks and language networks.The results showed that the functional connections of the brain network presented a series of repeated states of dense or sparse connections which have different temporal variation characteristics after stroke.It provides a new perspective and shows its potential advantages in study of stroke.This paper reviewed the current status of dynamic functional network connectivity which mainly focus on the functional connectivity properties of different brain networks,sensorimotor networks and language networks after stroke.

关 键 词：功能磁共振成像 动态功能连接 脑卒中 脑网络 

分 类 号：R445.2[医药卫生—影像医学与核医学] R743.3[医药卫生—诊断学]