中药湿热敷联合睑板腺按摩治疗睑板腺功能障碍临床研究  

Clinical Study on Chinese Medicine Wet Hot Compress Combined with Meibomian Gland Massage for Meibomian Gland Dysfunction

作　　者：欧阳云[1] 徐春龙[1] 高媛 顾全鑫 王珍珍 吴加亮[1] 刘正立[1] OUYANG Yun;XU Chunlong;GAO Yuan;GU Quanxin;WANG Zhenzhen;WU Jialiang;LIU Zhengli

机构地区：[1]南京中医药大学盐城附属医院眼科,江苏盐城224001

出　　处：《新中医》2021年第12期81-84,共4页New Chinese Medicine

基　　金：盐城市医学科技发展计划项目(YK2018032);盐城市中医院科研项目(YB201614)

摘　　要：目的:观察中药湿热敷联合睑板腺按摩治疗睑板腺功能障碍(MGD)的临床疗效。方法:将80例确诊为MGD的患者随机分为对照组和治疗组各40例。对照组采用常规西药治疗,治疗组在对照组治疗基础上采用软坚散结、清热活血中药湿热敷联合睑板腺按摩治疗。比较2组中医证候积分、泪膜破裂时间(BUT)及总有效率。结果:与同组治疗前比较,治疗4周、1个月、3个月后2组中医证候积分均降低(P<0.01),BUT值均增加(P<0.01)。与对照组治疗4周、1个月后比较,对照组治疗3个月后中医证候积分升高(P<0.01),BUT值降低(P<0.01)。与对照组治疗4周、1个月、3个月后比较,治疗组同期中医证候积分降低(P<0.05,P<0.01),同期BUT值增加(P<0.05,P<0.01)。治疗4周后,2组总有效率比较,差异无统计学意义(P>0.05)。与对照组治疗后3个月后比较,治疗组总有效率较高(P<0.05)。结论:软坚散结、清热活血中药湿热敷联合睑板腺按摩治疗MGD能取得较好的疗效。Objective:To observe the clinical effect of Chinese medicine wet hot compress combined with meibomian gland massage for meibomian gland dysfunction(MGD).Methods:A total of 80 cases of patients diagnosed with MGD were randomly divided into the control group and the treatment group,40 cases in each group.The control group was treated with routine western medicine,and the treatment group was additionally treated with Chinese medicine wet hot compress for softening hardness and dissipating binds as well as clearing heat and activating blood combined with meibomian gland massage based on the treatment of the control group.The Chinese medicine syndrome scores,the tear break-up time(BUT)and the total effective rate in the two groups were compared.Results:After four weeks,one month and three months of treatment respectively,the Chinese medicine syndrome scores in the two groups were decreased when compared with those before treatment(P<0.01),and BUT values were increased(P<0.01).Compared with those in the control group after four weeks and one month of treatment respectively,the Chinese medicine syndrome scores in the control group after three months of treatment were increased(P<0.01),and the BUT values were decreased(P<0.01).After four weeks,one month and three months of treatment respectively,the Chinese medicine syndrome scores in the treatment group were decreased when compared with those in the control group(P<0.05,P<0.01),and the BUT values were increased(P<0.05,P<0.01).After four-week treatment,there was no significant difference being found in the comparison of the total effective rates between the two groups(P>0.05).In three months after treatment,the total effective rate in the treatment group was higher than that in the control group(P<0.05).Conclusion:The therapy of Chinese medicine wet hot compress for softening hardness and dissipating binds as well as clearing heat and activating blood combined with meibomian gland massage for MGD can achieve better curative effect.

关 键 词：睑板腺功能障碍 中药湿热敷 睑板腺按摩 泪膜破裂时间 

分 类 号：R276.7[医药卫生—中医五官科学]