头孢唑啉酸与稀土元素Eu^(3+)配合物的合成及配位位置的研究  

A STUDY ON THE SYNTHESIS OF CEFAZOLIN COMPLEX WITH Eu^(3+) ION AND ITS COORDINATION SITES

作　　者：陈亮[1] 续浩[1] 穆丽璇 李敬霞 

机构地区：[1]山西大学分析测试中心,山西太原030006

出　　处：《波谱学杂志》2002年第4期365-370,共6页Chinese Journal of Magnetic Resonance

基　　金：山西省留学归国人员资助课题

摘　　要：头孢唑啉酸 (cefazolin)为抗生素类药物 ,它的钠盐就是通常所说的先锋霉素 .我们通过共沉淀法合成了头孢唑啉酸与稀土元素Eu3+ 的固体配合物 ,并对其进行了光谱及波谱研究 .通过IR、1 HNMR和1 3CNMR确定了配合物的配位点 ,并探讨了配位机理 .Cefazolin is an antibiotic, and sodium cefazolin is commonly known as cephalexin. Solid complex of cefazolin with Eu 3+ ion was synthesized in this study by the co-precipitation method. The complex synthesized was characterized by fluorescence spectroscopy, infrared spectroscopy (IR), thermal spectroscopy, scanning electron microscopic photographs and element analysis. The coordination sites of the complex and the mechanism of the complexing reaction were studied by IR, 1H NMR and 13C NMR.

关 键 词：EU^3+ 合成 配位位置 头孢唑啉酸 核磁共振 稀土元素 配合物 铕(Ⅲ) 抗生素类药物 

分 类 号：TQ465[化学工程—制药化工] TQ462.