Achieving broad-spectrum resistance against rice bacterial blight through targeted promoter editing and pathogen population monitoring  

作　　者：Jiyang Wang Yuese Ning Irene N.Gentzel Guo-Liang Wang 

机构地区：[1]State Key Laboratory for Biology of Plant Diseases and Insect Pests,Institute of Plant Protection,Chinese Academy of Agricultural Sciences,Beijing 100193,China [2]Department of Plant Pathology,The Ohio State University,Columbus,OH 43210,USA

出　　处：《aBIOTECH》2020年第2期119-122,共4页生物技术通报（英文版）

基　　金：We gratefully acknowledge grant supports from the National Natural Science Foundation of China(#31901829);the China Postdoctoral Science Foundation(2019M660894)to J.W.

摘　　要：Plant diseases severely reduce crop yields and threaten global food security.Broad-spectrum resistance(BSR)is a desirable trait because it confers resistance against more than one pathogen species or the majority of races/strains of the same pathogen.To control plant diseases,breeders have selected BSR to reduce disease occurrence and prolong the life-span of newly released cultivars in the last several decades(Mundt,Phytopathology 108(7):792–802,2018).Although effective,breeding of BSR cultivars in crop plants is still time-consuming and technically challenging.Recently,new gene-editing technologies such as CRISPR/Cas9 have dramatically accelerated the process of plant breeding and provided an approach for rapidly creating new varieties with BSR and other beneficial traits(Borrelli et al.,Front Plant Sci 9:1245,2018).In addition,close surveillance of pathogen populations in the field can provide useful information for the deployment of appropriate resistance genes in the target regions.In this mini-review,we focus on the significance and application of the exciting results from two recent companion papers published in Nature Biotechnology that provide new strategies to develop crop plants with BSR against pathogens through targeted promoter editing of susceptibility genes in plants as well as pathogen population monitoring.

关 键 词：CRISPR/Cas9 Broad-spectrum resistance Rice bacterial blight Stacking editing Pathogen population monitoring 

分 类 号：S435.111.47[农业科学—农业昆虫与害虫防治]