Amphiphilic Graft Copolymers of Hydroxypropyl Cellulose Backbone with Nonpolar Polyisobutylene Branches  

作　　者：Jin-Rui Deng Cong-Lei Zhao Zhi-Tao Wei Yi-Xian Wu 

机构地区：[1]State Key Laboratory of Chemical Resource Engineering,Beijing Advanced Innovation Center for Soft Matter Science and Engineering,Beijing Laboratory of Biomedical Materials,Beijing University of Chemical Technology,Beijing 100029,China

出　　处：《Chinese Journal of Polymer Science》2021年第8期1029-1039,I0007,共12页高分子科学（英文版）

基　　金：the National Natural Science Foundation of China(Nos.21574007 and 51521062);the Fundamental Research Funds for the Central Universities(Nos.XK1802-2 and XK1802-1).

摘　　要：The novel amphiphilic graft copolymers with hydrophilic hard polar hydroxypropyl cellulose(HPC)backbone and hydrophobic soft nonpolar polyisobutylene(PIB)branches have been successfully synthesized through nucleophilic substitution reaction of living PIB chains carrying oxonium ions with the-OH groups along HPC backbone.The PIB branch length in the graft copolymers could be designed by living cationic polymerization and the grafting density could be adjusted by PIB+/-OH molar ratio.The living PIB chains carrying oxonium ion were prepared by transformation of allyl bromide end groups in the presence of AgCI0_(4) and silver nanoparticles(3.2±0.3 nm,0.7 wt%-1.8 wt%)generated in situ from AgBr.The phase-separation morphology was formed in the graft copolymers due to their incompatibility between backbone and branches.The hydrophilicity on the surface of graft copolymer films could be turned to hydrophobicity by increasing grafting density or/and length of PIB branches.The soft PIB segments in graft copolymers provided an unique surface wa self-assembly for ant卜protein adsorption against bovine serum albumin.A small amount of Ag nanoparticles in the copolymers contributed to good antibacterial activities against Staphylococcus aureus or Escherichia coli.

关 键 词：Hydroxypropyl cellulose POLYISOBUTYLENE Graft copolymer Cationic polymerization 

分 类 号：TQ317[化学工程—高聚物工业]