心力衰竭新型生物标志物的研究  

Research on New Biomarkers of Heart Failure

作　　者：黎百志 李晓慧[1] 张爱文[1] LI Bai-zhi;LI Xiao-hui;ZHANG Ai-wen(Department of Cardiology,Affiliated Hospital of Chengde Medical University,Chengde 067000,Hebei,China)

机构地区：[1]承德医学院附属医院本部心脏内科,河北承德067000

出　　处：《医学信息》2021年第14期28-31,35,共5页Journal of Medical Information

摘　　要：心力衰竭(HF)是以心室重构、神经内分泌紊乱和外周血分布异常为特征的心血管疾病的终末期。随着人口老龄化及冠心病、糖尿病等疾病的患病率增加,心力衰竭患病率逐年增加,已成为社会经济发展的严重负担。由于心力衰竭的病理生理学机制复杂,常伴各种严重并发症及不良预后,因此对心力衰竭的早期识别及诊断十分重要。本文对目前心力衰竭的生物标志物研究现状进行综述。Heart failure(HF)is the terminal stage of cardiovascular disease characterized by ventricular remodeling,neuroendocrine disorders,and abnormal peripheral blood distribution.With the aging of the population and the increase in the prevalence of coronary heart disease,diabetes and other diseases,the prevalence of heart failure has increased year by year,which has become a serious burden for social and economic development.Since the pathophysiological mechanism of heart failure is complex,often accompanied by various serious complications and poor prognosis,it is very important for the early recognition and diagnosis of heart failure.This article reviews the current research status of biomarkers for heart failure.

关 键 词：心力衰竭 生物标志物 生长分化因子-15 半乳糖凝集素-3 

分 类 号：R541.6[医药卫生—心血管疾病]