芍药甘草汤化学成分及药理作用研究进展  

Research progress on chemical constituents and pharmacological activities of Shaoyao Gancao Decoction

作　　者：吴玲芳 李雨桐 唐迎紫 艾琳 张芮芹 王鑫国 牛丽颖 WU Lingfang;LI Yutong;TANG Yingzi;AI Lin;ZHANG Ruiqin;WANG Xinguo;NIU Liying(Hebei University of Traditional Chinese Medicine,College of Pharmacy,Shijiazhuang 050091,China;Hebei Traditional Chinese Medicine Formula Granule Engineering&Technology Innovate Center,Shijiazhuang 050091,China;Quality Evaluation&Standardization Engineering Research Center of Traditional Chinese Medicine,Shijiazhuang 050091,China)

机构地区：[1]河北中医学院药学院,河北石家庄050091 [2]河北省中药配方颗粒工程技术创新中心,河北石家庄050091 [3]河北省中药材品质评价与标准化工程研究中心,河北石家庄050091

出　　处：《药物评价研究》2021年第6期1354-1360,共7页Drug Evaluation Research

基　　金：河北省自然基金资助项目(H2019423050);河北省中医药管理局科研计划项目(2020130);河北省高等学校科学技术研究项目(QN2019119);河北中医学院科技能力提升项目(KTY2019068);河北中医学院博士科研基金(BZS2019001);河北中医学院优秀青年基金项目(YQ2020006)。

摘　　要：芍药甘草汤由白芍、炙甘草两味中药组成,具有调和肝脾、柔筋止痛等功效,是中医临床常用的缓急止痛之方。文献报道芍药甘草汤主要含有黄酮类、三萜皂苷类、单萜糖苷类、酚酸类、鞣质类、生物碱类、糖类等化学成分;药理研究表明芍药甘草汤具有解痉镇痛、保肝、抗炎、止咳、平喘、抗变态反应等药理作用。就近年来国内外对芍药甘草汤化学成分及药理作用的研究结果进行论述,为进一步综合开发利用奠定基础。Shaoyao Gancao Decoction, which is composed of paeonia lactiflora and honey-fried licorice root, has the functions of reconciling liver and spleen, soothing tendon and relieving pain. It is a commonly used prescription for relieving pain in traditional Chinese medicine. Literature reports that Shaoyao Gancao Decoction mainly contains flavonoids, triterpene glycosides, monoterpene glycosides, phenolic acids, tannins, alkaloids, saccharides and other chemical constituents. It has the pharmacological effects of antispasmodic and analgesic, liver protection, anti-inflammatory, anti-cough, anti-asthmatic, anti-allergic activities and so on. In this paper, the chemicals and pharmacological activities of Shaoyao Gancao Decoction were summarized to lay a foundation for further research.

关 键 词：芍药甘草汤 化学成分 药理作用 解痉镇痛 保肝 

分 类 号：R285.5[医药卫生—中药学]