冠状动脉狭窄程度与颈动脉粥样硬化的相关性分析  

The correlation analysis between the degree of coronary artery stenosis and carotid atherosclerosis

作　　者：刘超[1] 何翔[1] 张磊[2] 王艳平 王燕[1] 王佳[3] LIU Chao;HE Xiang;ZHANG Lei;WANG Yanping;WANG Yan;WANG Jia(Department of Diagnostic CT,Cangzhou Central Hospital,Cangzhou 061001,P.R.China;Department of MRI,Cangzhou Central Hospital,Cangzhou 061001,P.R.China;Department of Diagnostic Ultrasound,Cangzhou Central Hospital,Cangzhou 061001,P.R.China)

机构地区：[1]河北省沧州市中心医院CT诊断科,河北沧州061001 [2]河北省沧州市中心医院磁共振成像科,河北沧州061001 [3]河北省沧州市中心医院超声诊断科,河北沧州061001

出　　处：《医学影像学杂志》2021年第6期931-934,共4页Journal of Medical Imaging

基　　金：河北省卫生健康委员会医学科学研究青年科技课题(编号:20191270)。

摘　　要：目的分析冠心病患者冠状动脉狭窄程度与颈动脉粥样硬化病变损伤程度之间的相关性,探讨颈动脉超声对评估冠心病严重程度的临床意义。方法采用Gensini积分法评定冠心病患者的冠状动脉狭窄程度,将其分为轻度狭窄、中度狭窄和重度狭窄组。颈动脉超声观测其内中膜厚度(intima-media thickness,IMT)及粥样硬化斑块情况。统计分析三组冠心病患者颈动脉IMT、粥样硬化斑块个数、斑块总积分(Crouse积分法)、斑块总面积之间的差别;以及Gensini积分与颈动脉IMT、粥样硬化斑块个数、斑块总积分、斑块总面积的相关性。结果冠心病患者的Gensini积分、IMT、粥样硬化斑块个数、斑块总积分和斑块总面积,重度和中度狭窄组均明显大于轻度狭窄组(P<0.05),重度狭窄组又明显大于中度狭窄组(P<0.05);冠心病患者的Gensini积分与颈动脉IMT、粥样硬化斑块个数、斑块总积分、斑块总面积均呈正相关关系(P<0.05)。结论随着冠状动脉狭窄程度的增加,颈动脉粥样硬化病变程度也会随之加重。颈动脉超声对评估冠心病严重程度有指导意义。Objective To analyze the correlation between the degree of coronary artery stenosis and the severity of carotid atherosclerosis lesion of patients with coronary heart disease,and to explore the clinical significance of carotid ultrasound in assessing the severity of coronary heart disease.Methods The degree of coronary artery stenosis of patients with coronary heart disease was evaluated by Gensini integral method.The patients were divided into mild stenosis,moderate stenosis and severe stenosis groups.The intima-media thickness(IMT)and atherosclerotic plaque of carotid artery were measured by carotid ultrasound.The differences of carotid IMT,number of atherosclerotic plaques,total plaque score(Crouse integral method)and total plaque area among three groups of patients with coronary heart disease were statistically analyzed;The correlation analysis between Gensini score and carotid IMT,number of atherosclerotic plaques,total plaque score and total plaque area were also carried out.Results Among the Gensini score,IMT,number of atherosclerotic plaques,total plaque score and total plaque area,the moderate stenosis group and severe stenosis group were significantly higher than those of mild stenosis group(P<0.05),and those in the severe stenosis group were significantly higher than moderate stenosis group(P<0.05);There were positive correlations between Gensini score and carotid IMT,between Gensini score and atherosclerotic plaques,between Gensini score and total plaque score,between Gensini score and total plaque area(P<0.05).Conclusion With the increasing of coronary artery stenosis degree,the degree of carotid atherosclerosis is also increased.Carotid ultrasonography will play a guiding significance in evaluating the severity of coronary heart disease.

关 键 词：彩色多普勒超声 冠心病 GENSINI积分 内中膜厚度 颈动脉粥样硬化 

分 类 号：R445.1[医药卫生—影像医学与核医学] R543.4[医药卫生—诊断学]