Three new indole alkaloids from Rauvolfia yunnanensis  

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作  者:Yuan GAO Fei WANG Dong-Sheng ZHOU Yan LI Ji-Kai LIU 

机构地区:[1]State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,China [2]BioBioPha Co.,Ltd.,Kunming 650201,China [3]Graduate University of Chinese Academy of Sciences,Beijing 100049,China

出  处:《Natural Products and Bioprospecting》2011年第3期104-107,共4页应用天然产物(英文)

基  金:This work was financially supported by National Basic Research Program of China(973 Program)2009CB522300;the“West Light”program of Chinese Academy of Sciences,and Natural Product Library Program of BioBioPha.

摘  要:One rare tetracyclic macroline-type indole alkaloid,named rauvoyunine A(1),and two new picraline-type alkaloids rauvoyunines B and C(2 and 3)were isolated from the aerial parts of Rauvolfia yunnanensis.Their structures were elucidated on the basis of extensive spectroscopic analysis.Compounds 2 and 3 were evaluated for their in vitro cytotoxicity against five human tumor cell lines.

关 键 词:Rauvolfia yunnanensis indole alkaloid rauvoyunine 

分 类 号:O62[理学—有机化学]

 

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