Four new indole alkaloids from Plantago asiatica  

作　　者：Zhong-Hua GAO Ling-Mei KONG Xi-Sheng ZOU Yi-Ming SHI Shan-Zhai SHANG Huai-Rong LUO Cheng-Qin LIANG Xiao-Nian LI Yan LI Xue DU Wei-Lie XIAO Han-Dong SUN 

机构地区：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,Yunnan,China [2]University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Natural Products and Bioprospecting》2012年第6期249-254,共6页应用天然产物（英文）

基　　金：supported financially by the grants from the Chinese Academy of Sciences(KSCX2-EW-Q-10 and KSCX1-YW-R-24);the NSFC(No.20802082 and 30830115);the Major State Basic Research Development Program of China(No.2009CB522303 and 2009CB940900);the project of recruited top talent of sciences and technology of Yunnan Province(2006PY01-47).

摘　　要：Four new indole alkaloids,plasiaticines A-D(1-4),together with two known ones,were isolated from the seeds of Plantago asiatica.The structures of the new compounds were elucidated on the basis of comprehensive analysis of spectroscopic data.All compounds were tested for their cytotoxic activity,and all compounds except 4 were tested for their acetylcholinesterase(AChE)inhibitory activities.

关 键 词：Plantago asiatica indole alkaloid AChE inhibitory activity cytotoxic activity 

分 类 号：O62[理学—有机化学]