不同厂家茯苓配方颗粒红外光谱双指标序列法分析  

Study on Infrared Spectra of Poria cocos Formula Granule from Different Enterprises Based on Dual-index Sequence Analysis

作　　者：龙林 李清安 黄海华 胡辉 左刚 孙代华 LONG Lin;LI Qing-an;HUANG Hai-hua;HU Hui;ZUO Gang;SUN Dai-hua(Jing Brand Chizhengtang Pharmaceutical Co.,Ltd,Huangshi,Hubei^435100 China;Research Institute of Jing Brand,Huangshi,Hubei,435100 China;Hubei Provincial Key Lab for Quality and Safety of Traditional Chinese Medicine Health Food,Huangshi,Hubei,435100 China;Jing Brand Co.,Ltd,Daye,Hubei,435100 China)

机构地区：[1]劲牌持正堂药业有限公司,湖北黄石435100 [2]劲牌研究院,湖北黄石435100 [3]中药保健食品质量与安全湖北省重点实验室,湖北大冶435100 [4]湖北省中药配方颗粒工程技术研究中心,湖北大冶435100

出　　处：《时珍国医国药》2021年第3期589-591,共3页Lishizhen Medicine and Materia Medica Research

基　　金：国家重点研发计划(2017YFC1703006)。

摘　　要：目的比较不同厂家茯苓配方颗粒的质量差异。方法采用红外光谱结合共有峰率和变异峰率双指标序列法评价不同厂家茯苓配方颗粒与药材之间的相似性和差异性。结果茯苓配方颗粒与茯苓药材共有特征峰范围为:3381-3394,2921-2934,1637-1646,1369-1395,1077-1080,558-595cm-1;不同厂家茯苓配方颗粒的共有峰率和变异峰率存在差异,共有峰率在50.0%-66.7%,变异峰率在0-71.7%。结论茯苓配方颗粒与药材红外光谱的相似性和差异性不同,表明不同厂家茯苓配方颗粒质量存在明显差异,可为茯苓配方颗粒质量评价提供参考依据。Objective To evaluate the quality of different enterprises’ Poria cocos formula granule. Methods The Dual-indexes sequential analysis of the infrared spectra combined with common peak rate and variation peak rate was adopted to investigate the similarity and difference between Poria cocos and its formula granule. Results The ranges of the common characteristic peak are 381~3394, 2921~2934, 1637~1646, 1369~1395, 1077~1080, 558~595 cm-1;Respectively, the common peak rate and variation peak rate, which are different between Poria cocos and its formula granule, are 50.0% to 66.7%, and 0% to 71.7%. Conclusion There are various in similarity and difference, indicating the different quality, which can provide reference basis for quality evaluation of Poria cocos formula granules.

关 键 词：茯苓配方颗粒 红外光谱 共有峰率 变异峰率 质量差异 

分 类 号：R284.1[医药卫生—中药学] R283[医药卫生—中医学]