火热相关证候慢性失眠患者PSG特征的初步研究  

Preliminary study on PSG characteristics of chronic insomnia patients with fire and heat related syndrome

作　　者：党娇娇 于艺 张喜 袁霭凤[1] 雷洪涛[1] 闪增郁[1] 宋军[1] DANG Jiao-jiao;YU Yi;ZHANG Xi;YUAN Ai-feng;LEI Hong-tao;SHAN Zeng-yu;SONG Jun(Experimental Research Center,China Academy of Chinese Medical Sciences,Beijing,100100,China)

机构地区：[1]中国中医科学院医学实验中心,北京100700

出　　处：《时珍国医国药》2021年第3期646-648,共3页Lishizhen Medicine and Materia Medica Research

基　　金：中国中医科学院医学实验中心自主选题项目(zz2017010,zz2018015)。

摘　　要：目的运用多导睡眠监测仪探寻火热相关证候慢性失眠患者的多导睡眠图(PSG)特征。方法纳入16例辨证属肝郁化火证、阴虚火旺证与痰热内扰证的火热相关证候慢性失眠患者作为试验组,以20例健康受试者作为对照组,对两组受试者的PSG参数进行分析。结果试验组TST、R期、N2期时间、R%、SE低于对照组,SOL、WASO、W期时间、清醒次数、N1%、AHI高于对照组,差异具有统计学意义(P<0.05)。结论火热相关证候慢性失眠患者的PSG参数与健康人群存在明显差异,为火热相关证候慢性失眠的临床辨证提供客观可量化的标准。Objective To explore the characteristics of polysomnography(PSG) in chronic insomnia patients with fire and heat related syndrome by polysomnography. Methods 16 chronic insomnia patients with fire and heat related syndrome, covering depressed Gan transforming into fire, internal disturbance by phlegm-heat, excessive fire due to yin deficiency, were included in the test group, and 20 healthy subjects were taken as the control group. The PSG parameters of the two groups were analyzed.Results The TST, R, N2, R%, and SE were lower in the test group than in the control group, and the SOL, WASO, W, Awake times, N1%, and AHI were higher than those in the control group, with statistical significance(P<0.05).Conclusion There is a significant difference of PSG parameters between the chronic insomnia patients and the healthy people, providing an objective and quantifiable standard for the clinical syndrome differentiation of chronic insomnia with fire and heat related syndromes.

关 键 词：火热 慢性失眠 中医 证候 多导睡眠监测 

分 类 号：R256.23[医药卫生—中医内科学]