左氧氟沙星联合盐酸氨溴索治疗重症肺炎的效果分析  

Effect analysis of levofloxacin combined with ambroxol hydrochloride in the treatment of severe pneumonia

作　　者：庄承林 ZHUANG Chenglin(Puning Overseas Chinese Hospital,Puning 515300)

机构地区：[1]广东省普宁市普宁华侨医院,广东普宁515300

出　　处：《当代医药论丛》2021年第15期83-85,共3页

摘　　要：目的:探讨左氧氟沙星注射液联合盐酸氨溴索注射液治疗重症肺炎的效果。方法:选取2018年4月至2019年4月期间在广东省普宁市普宁华侨医院接受诊治的70例重症肺炎患者作为研究对象,将其分为对照组和试验组(35例/组)。对两组患者均使用左氧氟沙星注射液进行治疗。在此基础上,用盐酸氨溴索注射液对试验组患者进行治疗。然后比较两组患者治疗的总有效率、肺功能的各项临床指标及各项炎症因子的水平。结果:接受治疗后,与对照组患者相比,试验组患者治疗的总有效率及用力肺活量(FVC)、最大呼气中段流量(MMF)、最大呼气流量(PEF)的水平均更高,其血清白细胞介素-8(IL-8)、血清α肿瘤坏死因子(TNF-α)及血清降钙素原(PCT)的水平均更低,P<0.05。结论:用左氧氟沙星注射液联合盐酸氨溴索注射液治疗重症肺炎可改善其肺功能,减轻其炎性反应。Objective:To investigate the effect of levofloxacin injection combined with ambroxol hydrochloride injection in the treatment of severe pneumonia.METHODS:A total of 70 patients with severe pneumonia who received treatment in Puning Overseas Chinese Hospital of Puning City,Guangdong Province from April 2018 to April 2019 were selected as the research subjects,and divided into control group and experimental group(35 cases/group).Both groups were treated with levofloxacin injection.On this basis,the experimental group was treated with ambroxol hydrochloride injection.Then the total effective rate,the clinical indicators of lung function and the levels of inflammatory factors were compared between the two groups.Results:After treatment,the total response rate,forced vital capacity(FVC),maximum middle expiratory flow(MMF),and maximum expiratory flow(PEF)levels in the experimental group were higher than those in the control group.The levels of serum interleukin-8(IL-8),serum tumor necrosis factorα(TNF-α)and serum procalcitonin(PCT)were lower(P<0.05).Conclusion:levofloxacin injection combined with ambroxol hydrochloride injection in the treatment of severe pneumonia can improve lung function and reduce inflammatory r eaction.

关 键 词：重症肺炎 氨溴索 左氧氟沙星 

分 类 号：R563.1[医药卫生—呼吸系统]