New Azulene-Type Sesquiterpenoids from the Fruiting Bodies of Lactarius deliciosus  

作　　者：Michel Feussi Tala Jianchun Qin Joseph T.Ndongo Hartmut Laatsch 

机构地区：[1]Institute of Organic and Biomolecular Chemistry,University of Goettingen,Tammannstrasse 2,37077 Gottingen,Germany [2]School of Plant Science,Jilin University,Xian Road No.5333,Changchun 130062,Jilin,People’s Republic of China

出　　处：《Natural Products and Bioprospecting》2017年第3期269-273,共5页应用天然产物（英文）

基　　金：the Natural Science Foundation for a Chinese Government Scholarship Fund for Study Abroad(31470414,20140101126JC).

摘　　要：In the^(1)H NMR-guided fractionation of extracts from the edible mushroom Lactarius deliciosus,two new azulene-type sesquiterpenoids,7-isopropenyl-4-methyl-azulene-1-carboxylic acid(1)and 15-hydroxy-3,6-dihydrolactarazulene(2),together with seven known compounds were characterized.Their structures were determined on basis of spectroscopic evidence,as well as by comparing with literature data.Amongst the known metabolites,the^(13)C NMR assignment of 15-hydroxy-6,7-dihydrolactarazulene(3)is reported here for the first time.Moreover,7-acetyl-4-methylazulene-1-carbaldehyde(5)displayed a moderate antibacterial activity against Staphylococcus aureus.

关 键 词：Lactarius deliciosus Fungal pigments Azulene sesquiterpenoids Antibacterial activity 

分 类 号：O62[理学—有机化学]