Two New C21 Steroidal Glycosides from the Roots of Cynanchum paniculatum  

作　　者：Hai-Li Yu Qin Long Wen-Fang Yi Bao-Jia Yang Yu Song Xiao Ding Shun-Lin Li Xiao-Jiang Hao 

机构地区：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,People’s Republic of China [2]University of Chinese Academy of Sciences,Beijing 100049,People’s Republic of China

出　　处：《Natural Products and Bioprospecting》2019年第3期209-214,共6页应用天然产物（英文）

基　　金：supported financially by grants from the National Natural Science Foundation of China(Nos.31770389,81703393).

摘　　要：Two new C21 steroidal glycosides,paniculatumosides H and I,together with four known ones were isolated from the roots of Cynanchum paniculatum(Bge.)Kitag.Their structures were identifed by spectroscopic methods including extensive 1D and 2D NMR techniques.All compounds were subjected to detect the anti-tobacco mosaic virus(TMV)activities and their cytotoxities against three human tumor cell lines(SMMC-7721,MDA-MB-231 and A549).The results showed that compounds 1 and 5 exhibited potent protective activities against TMV,while 2,4 and 6 had moderate efects on the SMMC7721 cancer cells viability.

关 键 词：Cynanchum paniculatum Steroidal glycosides BIOACTIVITIES NMR data 

分 类 号：O62[理学—有机化学]