Diverse Polyphenols from Hypericum faberi  

作　　者：Xin-Wen Zhang Yan-Song Ye Fan Xia Xing-Wei Yang Gang Xu 

机构地区：[1]State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,Yunnan Key Laboratory of Natural Medicinal Chemistry,Kunming 650201,People’s Republic of China [2]University of Chinese Academy of Sciences,Beijing 100049,People’s Republic of China

出　　处：《Natural Products and Bioprospecting》2019年第3期215-221,共7页应用天然产物（英文）

基　　金：supported by the foundations from Kunming Institute of Botany(KIB2017001);Southeast Asia Biodiversity Research Institute(2017CASSEABRIQG003);CAS,and Yunnan Key Laboratory of Natural Medicinal Chemistry(S2017-ZZ11 and 2015-ZZ07).

摘　　要：Six new polyphenols with diferent isoprenylated xanthones,isoprenylated acylphloroglucinols,and chromone architectures,hyperfaberols A-F(1-6),were isolated from the whole plants of Hypericum faberi along with seven other related known compounds.In which hyperfaberols A/B(1/2)and 12-13 were isoprenylated xanthones,hyperfaberols C-E(3-5)and 8-11 were seven isoprenylated acylphloroglucinol derivatives,while 6-7 were two chromones.Their structures were elucidated by comprehensive analysis of their spectroscopic data as well as detailed comparison with the literature data.Compounds 1 and 11 showed cytotoxities against the human esophageal cancer cell line(ECA-109)and the pancreatic tumor cell line(PANC-1)in vitro,respectively.

关 键 词：Hypericum faberi Isoprenylated xanthone Isoprenylated acylphloroglucinol CHROMONE Cytotoxicitiy 

分 类 号：O62[理学—有机化学]