Chemical Constituents from Ethanoic Extracts of the Aerial Parts of Leea aequata L.,a Traditional Folk Medicine of Myanmar  

作　　者：Nay Lin Tun Dong-Bao Hu Meng-Yuan Xia Dong-Dong Zhang Jun Yang Thaung Naing Oo Yue-Hu Wang Xue-Fei Yang 

机构地区：[1]Southeast Asia Biodiversity Research Institute,Chinese Academy of Sciences,Yezin,Nay Pyi Taw 05282,Myanmar [2]Key Laboratory of Economic Plants and Biotechnology and the Yunnan Key Laboratory for Wild Plant Resources,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming 650201,People’s Republic of China [3]University of Chinese Academy of Sciences,Beijing 100049,People’s Republic of China [4]College of Resources and Environment,Yuxi Normal University,Yuxi 653100,People’s Republic of China [5]Forest Research Institute,Yezin,Nay Pyi Taw 05282,Myanmar

出　　处：《Natural Products and Bioprospecting》2019年第3期243-249,共7页应用天然产物（英文）

基　　金：supported by the Southeast Asia Biodiversity Research Institute,Chinese Academy of Sciences(Grant Nos.2015CASEABRIRG001 and Y4ZK111B01);the International Partnership Program of Chinese Academy of Sciences(153631KYSB20160004).

摘　　要：We aimed at reporting the chemical constituents and antimicrobial activities of Leea aequata L.,a traditional folk medicine used in Myanmar for the treatment of wounds and skin diseases.A new neolignan,(7S,8R)-9′-O-acetylcedrusin(1),a new lactam,(3S,4S)-4-chloro-3-hydroxypiperidin-2-one(2),along with 21 known compounds,including fve lignans(3-7),four favonoid glycosides(8-11),and others(12-23),were isolated from the ethanoic extract of the aerial parts of L.aequata.The structures of the new compounds were determined by NMR,MS,and ECD spectra.For all the antimicrobial tests of the 23 compounds,only 3,4,5-trihydroxybenzoic acid ethyl ester(17)showed weak inhibitory activities against Escherichia coli and Salmonella enterica subsp.enterica.

关 键 词：Leea aequata VITACEAE Traditional medicines Lignans FLAVONOIDS 

分 类 号：O62[理学—有机化学]