Secondary Metabolites Produced by an Endophytic Fungus Pestalotiopsis microspora  

作　　者：G.R.Nalin Rathnayake N.Savitri Kumar Lalith Jayasinghe Hiroshi Araya Yoshinori Fujimoto 

机构地区：[1]National Institute of Fundamental Studies,Hantana Road,Kandy,Sri Lanka [2]School of Agriculture,Meiji University,Kawasaki,Kanagawa 214‑8571,Japan

出　　处：《Natural Products and Bioprospecting》2019年第6期411-417,共7页应用天然产物（英文）

基　　金：Financial support from the National Research Council(Research Grant NRC 12–032)is gratefully acknowledged.

摘　　要：An endophytic fungus Pestalotiopsis microspora isolated from the fruits of Manilkara zapota was cultured in potato dextrose broth media.Chromatographic separation of the EtOAc extract of the broth and mycelium led to the isolation of a new azaphilonoid named pitholide E(1),in addition to previously identified pitholide B(2),pitholide D(3),pestalotin(LL-P880α)(4),PC-2(5),LL-P880β(6),tyrosol(7)and 4-oxo-4H-pyran-3-acetic acid(8).An endophytic fungus P.microspora from M.zapota and the isolation of compounds 1-5,7 and 8 from P.microspora are reported here for the first time.

关 键 词：Pestalotiopsis microspora Manilkara zapota ENDOPHYTE Pitholide E Pestalotin 

分 类 号：O62[理学—有机化学]